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ORIGINAL RESEARCH

Value of Methylation Status of RPRM, SDC2, and TCF4 Genes in Plasma for Gastric Adenocarcinoma Screening

ORCID Icon, , , ORCID Icon &
Pages 673-681 | Received 17 Nov 2022, Accepted 08 Feb 2023, Published online: 22 Feb 2023

Figures & data

Figure 1 Hub gene screening and analysis. (A) Venn diagram (The 3 datasets showed an overlap of 197 genes). (B) *TCF4 were statistically significant.

Figure 1 Hub gene screening and analysis. (A) Venn diagram (The 3 datasets showed an overlap of 197 genes). (B) *TCF4 were statistically significant.

Table 1 GO and KEGG Pathway Enrichment Analysis of DEGs in Stomach Cancer

Figure 2 Pathological morphology. (A) gastric adenocarcinoma HE X200 (B) gastritis HE X200.

Figure 2 Pathological morphology. (A) gastric adenocarcinoma HE X200 (B) gastritis HE X200.

Table 2 Basic Characteristics of Patients and Controls

Table 3 Results of Gastroscopy/Tissue Biopsy and Methylation of RPRM, SDC2, and TCF4 in Plasma

Figure 3 (A) methylation of RPRM, SDC2 and TCF4 were positive in GAC. (B) Internal reference ACTB express in gastritis.

Figure 3 (A) methylation of RPRM, SDC2 and TCF4 were positive in GAC. (B) Internal reference ACTB express in gastritis.