Demographic Factors Among HIV Confirmed Blood Donors from 2013 to 2021 in Shenzhen

Figures & data

Figure 1 The prevalence of HIV among unpaid blood donors from 2013 to 2021.

Table 1 The Prevalence of HIV Among Unpaid Blood Donors from 2013 to 2021

Group	HIV-Positive	HIV-Negative	Prevalence (Per 10,000 Persons)	HIV-Positive	HIV-Negative	Prevalence (Per 10,000 Persons)	χ^2	P value	OR(95% CI)
Gender	Male			Female
2013	31	40,353	7.7	1	23,677	0.4	15.732	<0.0001	18.189(2.483–133.248)
2014	49	42,314	11.6	1	25,966	0.4	25.527	<0.0001	30.069(4.152–217.764)
2015	40	45,984	8.7	4	26,879	1.5	14.599	<0.0001	5.845(2.091–16.339)
2016	38	48,266	7.9	1	29,296	0.3	20.560	<0.0001	23.065(3.167–167.997)
2017	35	54,287	6.4	2	28,647	0.6	13.888	<0.0001	9.235(2.221–38.397)
2018	22	53,947	4.1	1	30,823	0.3	10.185	0.001	12.570(1.694–93.257)
2019	26	58,009	4.5	2	34,058	0.6	10.702	0.001	7.633(1.811–32.159)
2020	25	59,067	4.2	2	33,978	0.6	9.868	0.002	7.191(1.703–30.359)
2021	34	63,422	5.3	5	35,950	1.4	9.212	0.002	3.854(1.507–9.856)
Age	<30			≥30
2013	17	9107	18.6	15	54,923	2.7	36.630	<0.0001	6.835(3.412–13.691)
2014	28	14,180	19.7	22	54,100	4.1	37.658	<0.0001	4.856(2.777–8.490)
2015	33	19,309	17.1	11	53,598	2.1	53.122	<0.0001	8.327(4.208–16.480)
2016	27	22,404	12.0	12	55,158	2.2	30.876	<0.0001	5.539(2.806–10.936)
2017	19	25,156	7.5	18	57,779	3.1	7.731	0.005	2.424(1.272–4.620)
2018	19	30,655	6.2	4	28,225	1.4	21.484	<0.0001	4.373(1.488–12.857)
2019	15	36,726	4.1	13	55,341	2.3	2.185	0.139	1.739(0.827–3.654)
2020	15	36,366	4.1	12	56,648	2.1	3.070	0.080	1.947(0.911–4.160)
2021	22	41,753	5.3	17	57,636	2.9	3.318	0.069	1.786(0.949–3.364)
Region	Local			Foreign
2013	6	17,067	3.5	26	46,834	5.5	1.035	0.309	1.539(0.261–0.633)
2014	5	16,202	3.1	45	51,989	8.6	5.224	0.022	0.357(0.142–0.898)
2015	7	17,410	4.0	37	55,359	6.7	1.553	0.213	0.602(0.268–1.350)
2016	4	17,965	2.2	35	59,453	5.9	3.668	0.055	1.064(0.134–0.378)
2017	3	20,664	1.5	34	62,159	5.5	5.603	0.018	0.265(0.082–0.864)
2018	2	21,391	0.9	21	63,356	3.3	3.336	0.068	0.282(0.066–1.203)
2019	5	22,754	2.2	23	69,239	3.3	0.711	0.399	0.662(0.251–1.740)
2020	5	26,962	1.9	22	66,088	3.3	1.434	0.231	0.557(0.211–1.471)
2021	3	26,160	1.1	36	73,212	4.9	6.980	0.008	0.233(0.072–0.757)
Education background	Lower			Higher
2013	21	35,040	6.0	11	28,961	3.8	1.527	0.217	1.578(0.761–3.273)
2014	35	38,948	9.0	15	29,322	5.1	3.420	0.064	1.757(0.959–3.217)
2015	28	42,103	6.6	16	30,756	5.2	0.617	0.432	1.278(0.692–2.363)
2016	21	43,649	4.8	18	33,895	5.3	0.095	0.758	0.906(0.483–1.701)
2017	25	44,767	5.6	12	38,152	3.1	2.745	0.098	1.775(0.892–3.534)
2018	17	45,086	3.8	6	39,679	1.5	3.966	0.046	2.494(0.983–6.325)
2019	18	47,906	3.8	10	44,150	2.3	1.682	0.195	1.659(0.766–3.594)
2020	16	43,431	3.7	11	45,649	2.4	1.192	0.275	1.529(0.709–3.295)
2021	17	47,009	3.6	22	52,363	4.2	0.216	0.642	0.861(0.457–1.621)
Donor State	First-time			Repeat
2013	21	55,337	3.8	11	8693	12.6	11.784	0.001	0.300(0.145–0.622)
2014	41	59,658	6.8	9	8622	10.3	1.307	0.253	0.658 (0.320–1.355)
2015	35	63,823	5.5	9	9040	9.9	2.620	0.106	0.551 (0.265–1.146)
2016	33	66,932	4.9	6	10,630	5.6	0.093	0.760	0.873 (0.366–2.085)
2017	30	71,621	4.2	7	11,313	6.2	0.874	0.350	0.677 (0.297–1.542)
2018	20	72,751	2.7	3	12,019	2.5	0.024	0.876	1.101 (0.327–3.707)
2019	19	78,783	2.4	8	13,285	6.0	3.894	0.048	0.400(0.175–0.915)
2020	17	42,995	4.0	10	50,055	2.0	3.049	0.081	1.979(0.906–4.323)
2021	32	49,724	6.4	7	49,687	1.4	16.001	<0.001	4.568(2.016–10.350)

Table 2 The Impact of COVID-19 on the Prevalence of HIV Among Different Blood Donors

Group			2019	2020	2021
Gender	Male	Positive	26	25	34
		Negative	58,009	59,067	63,422
		χ^2	0.042	–	0.369
		P value	0.838	–	0.808
		OR 95% CI	1.059 (0.612–1.834)		1.267 (0.756–2.123)
	Female	Positive	2	2	5
		Negative	34,058	33,978	35,950
		χ^2	<0.001	–	0.464
		P value	1.000	–	0.496
		OR 95% CI	0.998 (0.141–7.083)		2.363 (0.458–12.180)
Region	Local	Positive	5	5	3
		Negative	22,754	26,962	26,160
		χ^2	<0.001	–	0.097
		P value	1.000	–	0.756
		OR 95% CI	1.185 (0.343–4.094)		0.618 (0.148–2.588)
	Foreign	Positive	23	22	36
		Negative	69,239	66,088	73,212
		χ^2	<0.001	–	2.104
		P value	0.994	–	0.147
		OR 95% CI	0.998 (0.556–1.790)		1.477 (0.869–2.511)
Education background	Lower	Positive	18	16	17
		Negative	47,906	43,431	47,009
		χ^2	0.003	–	0.003
		P value	0.954	–	0.958
		OR 95% CI	1.020 (0.520–2.000)		0.982 (0.496–1.943)
	Higher	Positive	10	11	22
		Negative	44,150	45,649	52,363
		χ^2	0.020	–	2.325
		P value	0.887	–	0.127
		OR 95% CI	0.940 (0.399–2.213)		1.744 (0.845–3.596)
Donor status	First-time	Positive	19	17	32
		Negative	78,783	42,995	49,724
		χ^2	2.237	-	2.685
		P value	0.135	-	0.101
		OR 95% CI	0.610 (0.317–1.174)		1.984 (1122–3.507)
	Repeat	Positive	8	10	7
		Negative	13,285	50,055	49,687
		χ^2	4.647	-	0.507
		P value	0.031	-	0.476
		OR 95% CI	3.014 (1.189–7.639)		0.705 (0.268–1.853)
Age	18–29	Positive	15	15	22
		Negative	36,726	36,366	41,753
		χ^2	0.001	-	0.537
		P value	0.978	-	0.464
		OR 95% CI	0.990 (0.484–2.026)		1.277 (0.663–2.463)
	30–65	Positive	13	12	17
		Negative	55,341	56,648	57,636
		χ^2	0.067	-	0.778
		P value	0.796	-	0.378
		OR 95% CI	1.109 (0.506–2.430)		1.392 (0.665–2.916)

Figure 2 The prevalence of HIV among male and female blood donors from 2013 to 2021.

Table 3 The Impact of COVID-19 on the Structure of Blood Donors

Group		2019	2020	2021
Gender	Male	58,035 (63.02%)	59,092 (63.49%)	63,456 (63.83%)
	Female	34,060 (36.98%)	33,980 (36.51%)	35,955 (36.17%)
	χ^2	4.478	–	2.421
	P value	0.034	–	0.120
	OR 95% CI	0.980 (0.961–0.998)		1.015 (0.996–1.034)
Region	Locals	22,759 (24.73%)	26,967 (28.97%)	26,163 (26.32%)
	Foreigners	69,262 (75.27%)	66,110 (71.03%)	73,248 (73.68%)
	χ^2	423.477	–	169.537
	P value	<0.001	–	<0.0.001
	OR 95% CI	0.806 (0.789–0.822)		0.876 (0.858–0.893)
Education background	Lower	47,924 (52.04%)	43,447 (46.84%)	47,026 (47.30%)
	Higher	44,160 (47.96%)	49,304 (53.16%)	52,385 (52.70%)
	χ^2	500.075	–	4.111
	P value	<0.001	–	0.043
	OR 95% CI	1.232 (1.209–1.254)		1.019 (1.001–1.037)
Donor status	First-time	78,802 (85.57%)	43,012 (46.21%)	49,724 (50.02%)
	Repeat	13,293 (14.43%)	50,065 (53.79%)	49,687 (49.98%)
	χ^2	31,852.996	–	279.106
	P value	<0.001	–	<0.001
	OR 95% CI	6.900 (6.747–7.057)		1.165 (1.144–1.186)
Age	18–29	36,741 (39.89%)	36,381 (39.10%)	41,775 (42.02%)
	30–65	55,354 (60.11%)	56,660 (60.90%)	57,636 (57.98%)
	χ^2	12.166	–	169.950
	P value	<0.001	–	<0.001
	OR 95% CI	1.034 (1.015–1.053)		1.129 (1.108–1.150)