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International Journal of General Medicine Volume 16, 2023 - Issue
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Latest Trends in Retinopathy of Prematurity: Research on Risk Factors, Diagnostic Methods and Therapies

Laura Bujoreanu Bezman1 Department of Ophthalmology, “Sfantul Apostol Andrei” Emergency Clinical Hospital, Galati, Romania;2 Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaView further author information
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Carmen Tiutiuca1 Department of Ophthalmology, “Sfantul Apostol Andrei” Emergency Clinical Hospital, Galati, Romania;3 Clinical Surgical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaCorrespondence[email protected]
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Geanina Totolici1 Department of Ophthalmology, “Sfantul Apostol Andrei” Emergency Clinical Hospital, Galati, Romania;3 Clinical Surgical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaView further author information
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Nicoleta Carneciu1 Department of Ophthalmology, “Sfantul Apostol Andrei” Emergency Clinical Hospital, Galati, Romania;2 Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaView further author information
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Florin Ciprian Bujoreanu4 Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3029-9245View further author information
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Diana Andreea Ciortea5 Department of Pediatrics, “Sfantul Ioan” Emergency Clinical Hospital for Children, Galati, Romania;6 Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaView further author information
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Elena Niculet2 Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, Romania;4 Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaORCID Iconhttps://orcid.org/0000-0001-9249-5247View further author information
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Ana Fulga3 Clinical Surgical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, Romania;4 Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaView further author information
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Anamaria Madalina Alexandru4 Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, Romania;7 Department of Neonatology, “Sfantul Apostol Andrei” Emergency Clinical Hospital, Galati, RomaniaView further author information
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Daniela Jicman Stan4 Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaORCID Iconhttps://orcid.org/0000-0001-5278-962XView further author information
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Aurel Nechita5 Department of Pediatrics, “Sfantul Ioan” Emergency Clinical Hospital for Children, Galati, Romania;6 Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galati, RomaniaView further author information
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Pages 937-949 | Received 12 Dec 2022, Accepted 17 Feb 2023, Published online: 14 Mar 2023

Figures & data

Figure 1 Schematic representation of the risk factors of ROP.

Abbreviation: IGF-1, insulin-like growth factor 1.
Figure 1 Schematic representation of the risk factors of ROP.

Figure 2 Schematic representation of the interaction between oxygen, IGF-1, VEGF and the development of retinal vessels in ROP.

Abbreviations: IGF-1, insulin-like growth factor 1; VEGF, vascular endothelial growth factor.
Figure 2 Schematic representation of the interaction between oxygen, IGF-1, VEGF and the development of retinal vessels in ROP.

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