Factors Affecting the Delay of intravenous Thrombolysis in Hyperacute Ischemic Stroke Patients: A Single Centre Study

Figures & data

Table 1 Demographic Characteristics of Ischemic Stroke Patients

Demographic Characteristic	“Delay” (n=118)	“Non-Delay” (n=23)	P-value
Average age ± std (year)	58.29±11.19	55.57±15.55	0.112
Gender (n, %)			0.029*
Male	75 (64%)	9 (39%)
Female	43 (36%)	14 (61%)
Risk factors (n, %)
Hypertension	80 (67.8%)	13 (56.5%)	0.297
Dyslipidemia	51 (43.2%)	5 (21.7%)	0.047*
Hyperuricemia	6 (5.1%)	0	0.043*
Hypercoagulation	4 (3.4%)	1 (4.3%)	0.82
Diabetes Mellitus	26 (22%)	5 (21.7%)	0.96
Smoking	36 (30.5%)	6 (26.1%)	0.671
Rheumatic Heart Disease	3 (2.5%)	1 (4.3%)	0.633
Previous stroke	13 (11%)	1 (4.3%)	0.328
Atrial Fibrillation	14 (11.9%)	6 (26.1%)	0.074
Chronic Kidney Disease	2 (1.7%)	0	0.529
Coronary Heart Disease	9 (7.6%)	0	0.169

Note: *Statistically significant.

Table 2 Clinical Characteristics of Intravenous Thrombolysis Patients

Clinical Characteristic	“Delay” (n=118)	“Non-Delay” (n=23)	P-value
Onset	39.97±64.30	3.11±0.94	<0.001*
Clinical manifestation (n, %)
Limb weakness	113 (95.76%)	22 (95.65%)	0.981
Speech disorder	67 (56.78%)	10 (43.48%)	0.241
Sensory disorder	29 (24.58%)	3 (13.04%)	0.227
Loss of consciousness	60 (50.85%)	14 (60.87%)	0.379
Seizure	8 (6.78%)	2 (8.7%)	0.743
Mean NIHSS on admission	10.65 ± 5.08	11.96 ± 5.00	0.264
Mean NIHSS on discharge	4.82 ± 4.55	4.7 ± 4.96	0.905

Note: *Statistically significant.

Table 3 Regression Logistics of Delayed Intravenous Thrombolysis Patients

Variable Predictor	Standard Error	Odds Ratio	95% CI	P-value
Gender (male)	0.477	2.592	1.04–1.17	0.046*
Dyslipidemia	0.613	0.293	1.12–1.30	0.045*
Hyperuricemia	0.844	2.779	1.10–1.23	0.226
Onset	0.001	2.521	−0.002–0.00	0.007*

Note: *Statistically significant.