Comparison of Dydrogesterone and GnRH-a Effects After Laparoscopic Surgery in Patients with Stage III and IV Endometriosis

Figures & data

Table 1 General Patient Data

General Information	Dydrogesterone Group (n = 70)	GnRH-a Group (n = 81)	P value
Age (years, Mean ± SD)	29.2 ± 3.7	29.6 ± 3.2	0.472
Body mass index (kg/m^2, Mean ± SD	20.4 ± 2.1	20.4 ± 2.6	0.560
Number of pregnancies (range/median)	0–5/0	0–4/0	0.196
Parity (range/median)	0–1/0	0–3/0	0.992
Infertility (n)	42	55	0.314
Dysmenorrhea (n)	48	51	0.470
CA125 (U/mL, Mean ± SD)	49.0 ± 44.4	52.7 ± 40.3	0.498
Max. diameter of endometriomas (cm, Mean ± SD)	4.9 ± 2.1	4.8 ± 2.3	0.666
Side of endometriomas, n (%)			0.468
Left side	28 (40.0%)	24 (29.6%)
Right side	16 (22.9%)	27 (33.3%)
Bilateral	26 (37.1%)	30 (37.1%)
Uterine cavity depth (cm,   Mean ± SD)	7.5 ± 0.6	7.6 ± 0.6	0.318
Preoperative uterine rectal fossa patency, n (%)			0.728
Open	17 (24.3%)	16 (19.8%)
Partially closed	24 (34.3%)	31 (38.3%)
Completely enclosed	29 (41.4%)	34 (41.9%)
r-AFS staging, n (%)			0.541
III	24 (34.3%)	24 (29.6%)
IV	46 (65.7%)	57 (70.4%)

Table 2 Spontaneous Pregnancy Rates in the Two Groups

Pregnancy Outcome	Dydrogesterone Group (n, %)		GnRH-a Group (n, %)
Pregnancy	31	44.3	18	22.2
Non-pregnant	39	55.7	63	77.8
X^2 Value	8.339
P value	0.005

Figure 1 Cumulative spontaneous pregnancy rates in both groups.