Clinical Application of Serum Interleukin-6 Combined with Inflammatory Cytokines in the Dynamic Monitoring of Patients with Acute Cholecystitis

Figures & data

Table 1 Expression Levels of Serum Cytokines in Patients with Acute Cholecystitis at Different Time Points

	Group	N	1st day	3rd day	5th day	7th day
IL 6 (ng/mL)	M-C group	60	34.52±2.57	25.61±2.84	10.96±1.22	5.42±0.85
	MS-C group	40	93.82±16.51	53.53±5.57	38.75±4.87	20.76±2.64
P value			<0.001***	<0.001***	<0.001***	<0.001***
IL 2 (ng/mL)	M-C group	60	3.52±0.98	3.26±1.01	3.17±0.79	3.14±0.58
	MS-C group	40	4.12±1.34	3.64±1.31	3.46±1.09	3.42±0.96
P value			0.012*	0.104	0.126	0.072
IL 4 (ng/mL)	M-C group	60	2.25±0.83	2.09±0.61	2.11±0.67	2.03±0.52
	MS-C group	40	2.31±0.92	2.30±0.74	2.21±0.68	2.24±0.65
P value			0.735	0.125	0.525	0.077
IL 10 (ng/mL)	M-C group	60	10.94±3.14	9.98±2.13	7.18±2.07	6.93±2.10
	MS-C group	40	13.57±6.87	11.54±4.61	8.51±3.71	7.81±2.30
P value			0.011*	0.025*	0.023*	0.051
TNFα (ng/mL)	M-C group	60	2.14±0.76	2.03±0.51	1.98±0.47	2.01±0.50
	MS-C group	40	2.21±0.86	2.17±0.81	2.19±0.76	2.08±0.83
P value			0.670	0.291	0.091	0.600
IFNγ (ng/mL)	M-C group	60	1.71±0.43	1.63±0.49	1.68±0.37	1.59±0.40
	MS-C group	40	1.89±0.51	1.72±0.48	1.70±0.42	1.74±0.47
P value			0.060	0.367	0.803	0.090

Notes: M-C group represents mild acute cholecystitis patients, MS-C group represents moderate-to-severe acute cholecystitis patients. Data are presented as mean ± SD. *P < 0.05, ***P < 0.001, significantly different from the values in M-C group.

Figure 1 The expression levels of serum procalcitonin (PCT) concentrations in patients with acute cholecystitis at different time points. M-C group represents mild acute cholecystitis patients, MS-C group represents moderate-to-severe acute cholecystitis patients. Data are presented as mean ± SD. ***P < 0.001, significantly different from the values in M-C group.

Figure 2 The neutrophil count in the serum of patients with acute cholecystitis at different time points. M-C group represents mild acute cholecystitis patients, MS-C group represents moderate-to-severe acute cholecystitis patients. Data are presented as mean ± SD. **P < 0.01, significantly different from the values in M-C group.

Figure 3 Receiver operating characteristic (ROC) curves analysis of serum IL-6 and PCT levels and neutrophil counts in patients with acute cholecystitis.