Retinoblastoma Incidence in Taiwan Over a Recent 20-Year Period: A Comprehensive Nationwide Study

Figures & data

Figure 1 The patients’ selection of the study.

Table 1 Demographic Information of Retinoblastoma in Taiwan During 1999 to 2018, Total Candidate Participants

Variable	N	%
Overall	248	100.00
Age group
<2	183	73.79
≥2	65	26.21
Gender
Male	134	54.03
Female	114	45.97
Treatment
Without any treatment	17	6.85
Operation	193	77.82
Radiation therapy	25	10.08
Chemotherapy	113	45.56
Regional chemotherapy	33	13.31

Figure 2 Number of cases and ratio between sex by diagnostic age in Taiwan during 1999 to 2018, total candidate participants.

Table 2 Incidence of Retinoblastoma in Taiwan During 1999 to 2018, Total Candidate Participants (N = 248)

Demographic Variable	Number of Cases	Percentage	Incidence Rate*	Relative Risk (95% CI)
Overall	248	100.00	60.20	–
Sex
Male	134	54.03	62.44	Ref.
Female	114	45.97	57.75	0.92 (0.72–1.19)
Birth year
1999–2003	67	27.02	53.03	Ref.
2004–2008	65	26.21	66.68	1.26 (0.89–1.77)
2009–2013	67	27.02	72.04	1.36 (0.97–1.91)
2014–2018	49	19.76	51.49	0.97 (0.67–1.40)

Notes: *Incidence rate is the number of cases divided by per million live births.

Figure 3 Incidence Trend of Retinoblastoma from 1999 to 2018. (A). Overall; (B). different age population; (C). different sex population; *p<0.05.