Can We Predict the Grade of Clear Cell Renal Cell Carcinoma from Houns-Field Unit of Renal Lesion on Computerized Tomography Scan, a Retrospective Cross-Sectional Study

Figures & data

Figure 1 Clear Cell Renal Cell Carcinoma. 47-year-old male. (a) Non-contrast axial CT scan, with a mass in the upper pole of the Lt Kidney. Mean HU=16.15. (b) Post-contrast nephrogenic phase axial CT scan with the mass in the upper pole of the Lt Kidney. Mean HU= 63.74.

Table 1 Illustration for Demographics, Smoking Status, Tumor Size, Grades and HU in Pre-Contrast and Nephrogenic Phase

Characteristic	N	Percent	Mean	Range	SD
Sex
Male	82	66.7	–	–	–
Female	41	33.3	–	–	–
Age (years)	–	–	63.02	39–83	±8.91
Smoking	98	79.7	–	–	–
Tumor
Size (cm)	–	–	6.31	2–19	±3.42
Hounsfield unit without contrast	–	–	29.14	12–48	±8.10
Hounsfield unit Nephrogenic phase	–	–	87.78	35–151	±23.15
Hounsfield unit difference	–	–	58	19–137	±21.96
Grading
Low grade (grade 1 and grade 2)	70 (9+61)	56.9	–	–	–
High grade (grade 3 and grade 4)	53 (37+16)	43.1	–	–	–

Table 2 Different Variables and Their P values

Variables List	p-value
HU without contrast	0.001
HU nephrogenic phase	0.037
HU difference	0.641
Age	0.794
Size of tumor	0.001
Sex	0.607
Smoking	0.056

Notes: The dependent value was the tumour grade. For the independent samples, t tests were used for the numerical variables, and chi-square tests were used for the categorical variables Differences were considered statistically significant at p < 0.05.