Predictive Value of the Neutrophil-to-Lymphocyte Ratio and C-Reactive Protein in Patients with Idiopathic Facial Nerve Palsy

Figures & data

Table 1 Comparing the General Data Between the Two Groups

Characteristics	Good Prognosis Group (n=69)	Poor Prognosis Group (n=25)	t/χ^2/Z	P
Age, y	43[34, 52.5]	40[28, 56.5]	0.617	0.537
Male, n (%)	35(50.7)	15(60.0)	0.634	0.426
Hypertension, n (%)	10(14.5)	5(20.0)	0.415	0.519
BMI (kg/m^2)	21.4±3.8	24.3±5.5	3.402	0.005
Left side, n (%)	49(71.0)	18(72.0)	0.009	0.926
Portmann score	8.4±2.3	7.2±2.4	2.246	0.027
H-B score	3.5[2, 4.5]	4[2, 5]	2.124	0.034
CRP (mg/l)	5[9, 15]	13[7, 19.5]	1.994	0.046
NLR	3.25±0.78	4.41±1.06	5.772	<0.001
Antivirus, n(%)	10 (14.5)	3 (12.0)	0.098	0.754

Notes: t, t test; χ^2, chi-square test; Z, Mann–Whitney U-test.

Abbreviations: BMI, body mass index; CRP, C-reactive protein; H-B, House-Brackmann; NLR, neutrophil-to-lymphocyte ratio.

Table 2 Logistic Regression Analysis of the Clinical Outcome of Patients with Idiopathic Facial Palsy

	β	SE	Wald	P	OR	95% CI
BMI	0.010	0.017	0.379	0.538	1.010	0.978–1.043
Portmann scores	0.228	0.233	3.841	0.045	1.268	1.005–1.616
NLR	−1.340	0.364	13.750	0.000	0.262	0.128–0.533
CRP	−0.042	0.126	2.625	0.049	0.949	0.895–0.989

Abbreviations: BMI, body mass index; NLR, neutrophil-to-lymphocyte; CRP, C-reactive protein. Ratio; SE, standard error; OR, odds ratio; CI, confidence interval.

Table 3 Relationship Between Different Item Scores and Functional Prognosis in the Portmann Scores

score>1 n (%)	Raising Eyebrows	Closing Eyes	Widening Nostrils	Pursing Mouth	Showing Teeth	Bulging Cheeks
Good prognosis (n=69)	38(56.7)	18(26.1)	41(59.4)	24(34.8)	19(27.5)	16(23.2)
Poor prognosis (n=25)	8(32.0)	8(32.0)	8(32.0)	4(16.0)	5(20.0)	2(8.0)
χ^2	4.449	0.321	5.793	3.095	0.548	2.734
P	0.035	0.571	0.016	0.079	0.459	0.140

Table 4 Predictive Efficacy of NLR and CRP Levels on the Outcome of Idiopathic Facial Nerve Palsy

	AUC	P	95% CI
NLR	0.764	<0.001	0.643–0.884
CRP	0.697	0.004	0.590–0.850
NLR+CRP	0.829	<0.001	0.733–0.924

Abbreviations: NLR, neutrophil-to-lymphocyte ratio; CRP, C-reactive protein; AUC, area under curve; CI, confidence interval.

Figure 1 ROC of NLR and CRP levels on poor neurologic prognosis in patient with idiopathic facial nerve palsy.

Abbreviations: NLR, neutrophil-to-lymphocyte ratio; CRP, C-reactive protein.