Study of urinary leukotriene E₄ levels in children with acute asthma

Figures & data

Table 1 General characteristics of the studied groups

Variable	Group I	Group II
Age	7.9±3.5	6.7±3.3
Sex
Male	43 (68.3%)	18 (31.7%)
Female	20 (72.0%)	7 (28.0%)
Total	63	25

Table 2 Level of urinary LTE₄ (pg/mg creatinine) according to asthma severity

LTE4	Mean ± SD	t	P
Severity
Mild (n=35)	247.8±30.1	t1=13	P<0.001
Moderate (n=20)	336.5±20.2	t2=7.67	P<0.001
Severe (n=8)	513.3±96.9	t3=5.12	P<0.001

Notes: t1, mild versus moderate; t2, mild versus severe; t3, moderate versus severe.

Abbreviations: LTE₄, leukotriene E₄; SD, standard deviation.

Table 3 TS IgE (IU/mL) levels according to asthma attack severity

TS IgE	X ± SD	t	P-value
Severity
Mild (n=35)	242.1±154.1	t1=2.83	P<0.01
Moderate (n=20)	395.7±213.1	t2=14.1	P<0.001
Severe (n=8)	1,039.2±141.3	t3=9.32	P<0.001

Notes: t1, mild versus moderate; t2, mild versus severe; t3, moderate versus severe.

Abbreviations: TS IgE, total serum IgE; SD, standard deviation.

Figure 1 Correlation between urinary LTE₄ and TS IgE among group I.

Abbreviations: IgE, immunoglobulin E; LTE₄, leukotriene E₄.