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International Journal of Interferon, Cytokine and Mediator Research Volume 6, 2014 - Issue
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Review

Inflammatory bowel disease: a focus on the involvement of dietary fats

Punyanganie S de Silva1 Department of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital;2 Harvard Medical School, Boston, MA, USACorrespondence[email protected]
&
Joshua R Korzenik1 Department of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital;2 Harvard Medical School, Boston, MA, USA
Pages 19-25 | Published online: 22 Jul 2014

Figures & data

Figure 1 Schematic diagram of key n-3 and n-6 PUFA-metabolism pathways associated with inflammation in inflammatory bowel disease.

Notes: *Proinflammatory pathway. Some metabolites have been omitted to reduce complexity.
Abbreviations: PUFA, polyunsaturated fatty acid; FADS, fatty acid desaturase; CYP, cytochrome P450; COX, cyclooxygenase; LOX, lipoxygenase; PG, prostaglandin; LT, leukotriene; TX, thromboxane.
Figure 1 Schematic diagram of key n-3 and n-6 PUFA-metabolism pathways associated with inflammation in inflammatory bowel disease.

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