Figures & data
Figure 1 Morphology and particle size features of AgNPs.
Notes: TEM (A), particles size distribution (B), SEM (C) documentation of AgNPs morphology.
Abbreviations: TEM, transmission electron microscope; SEM, scanning electron microscope; AgNPs, silver nanoparticles.
Figure 2 Effects of AgNPs on the growth of H1299 cells.
Abbreviation: AgNPs, silver nanoparticles.
Figure 3 Effects of AgNPs on apoptosis of H1299 cells.
Notes: Representative pictures are shown in A (control), B (10 μg/mL AgNPs induced), and C (20 μg/mL AgNPs induced). (D) The percentage of apoptosis cells by different concentrations of AgNPs. The arrow is indicated as the apoptotic cells with the classical morphological features such as cell shrinkage, nuclear condensation, and formation of apoptotic bodies.
Abbreviation: AgNPs, silver nanoparticles.
Figure 4 Inhibitory effects of AgNPs on NF-κB transcriptional activity in PC-3/N cells.
Abbreviations: AgNPs, silver nanoparticles; NF-κB, nuclear factor-kappa B.
Figure 5 Effects of AgNPs on the expression of phosphorylated stat3, bcl-2, and caspase in H1299 cells.
Abbreviation: AgNPs, silver nanoparticles.
Figure 6 Effects of ip administration of AgNPs on the progression and growth of H1299 tumors.
Notes: (A) Growth curve of H1299 tumors in each group. Each value is mean ± SE from eight mice. (B) Individual body weight of mice after treatment for 28 days. *P<0.05.
Abbreviations: AgNPs, silver nanoparticles; ip, intraperitoneal.
Figure 7 Effects of ip administration of AgNPs on the development and growth of H1299 tumors.
Notes: (A) Growth curve of H1299 tumors in each group. Each value represents mean ± SE from nine mice. (B) Individual body weight of mice after treatment for 36 days. **P<0.01.
Abbreviations: AgNPs, silver nanoparticles; ip, intraperitoneal.
