Establishment of a biophysical model to optimize endoscopic targeting of magnetic nanoparticles for cancer treatment

Figures & data

Figure 1 Magnetic field of a single coil in two different planes calculated by the developed programming routine in MATLAB^®.

Note: Unit of measurement is cm.

Figure 2 Weighting factors in different areas for prostate cancer: brown, tumor area; green, healthy prostate gland; light blue, surrounding area outside the prostate gland; and dark blue, region far away from tumor.

Note: Unit of measurement is cm.

Figure 3 Hermetically sealed capsules with tissue, fixed with cotton wool and placed in plastic tubes.

Figure 4 Magnetic moments of native porcine tissue dependent on applied magnetic field strength (conversion of Gaussian units to SI units: 1emu =10⁻³ Am² ;$1\text{Oe=}\frac{{10}^3}{4\pi }\frac{A}{m}$).

Figure 5 Biophysical model in MATLAB^® for adenocarcinoma of the esophagus and CT scan (A), and prostate cancer with borders of the prostate, the urethra and the rectum (B).

Abbreviation: CT, computed tomography.

Figure 6 Optimized coil configuration with resulting magnetic field for prostate cancer (A) and esophageal cancer (B).

Note: Unit of measurement is cm.