Figures & data
Figure 1 FT-IR spectrum of O-CNT and O-CNT-PEG.
Abbreviations: au, absorbance units; FT-IR, Fourier Transform infrared; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol.
![Figure 1 FT-IR spectrum of O-CNT and O-CNT-PEG.Abbreviations: au, absorbance units; FT-IR, Fourier Transform infrared; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol.](/cms/asset/f12f5c37-f7ad-4276-bb1c-d48edf941def/dijn_a_134661_f0001_c.jpg)
Figure 2 TGA thermo grams of O-CNT and O-CNT-PEG.
Abbreviations: au, absorbance units; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; TGA, thermogravimetric analysis.
![Figure 2 TGA thermo grams of O-CNT and O-CNT-PEG.Abbreviations: au, absorbance units; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; TGA, thermogravimetric analysis.](/cms/asset/64164dca-f28b-4afc-abcc-3fc2a78b0e96/dijn_a_134661_f0002_c.jpg)
Figure 3 FESEM images of functionalized CNTs.
Notes: (A) O-CNT and (B) O-CNT-PEG.
Abbreviations: FESEM, field emission scanning electron microscopy; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; CNT, carbon nanotubes.
![Figure 3 FESEM images of functionalized CNTs.Notes: (A) O-CNT and (B) O-CNT-PEG.Abbreviations: FESEM, field emission scanning electron microscopy; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; CNT, carbon nanotubes.](/cms/asset/7a2672b3-4bb8-491b-b7e9-439213146485/dijn_a_134661_f0003_b.jpg)
Figure 4 UV–Vis absorption spectrum of O-CNT-PEG.
Abbreviations: au, absorbance units; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; UV–Vis, ultraviolet–visible.
![Figure 4 UV–Vis absorption spectrum of O-CNT-PEG.Abbreviations: au, absorbance units; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; UV–Vis, ultraviolet–visible.](/cms/asset/f993614b-abec-46d0-b1d8-c1467fb607fc/dijn_a_134661_f0004_b.jpg)
Figure 5 MTT assay of MWNT. O-CNT, and O-CNT-PEG against HepG2 (A) and HeLa (B) cell lines.
Abbreviations: Conc, concentration; MWNT, multiwalled carbon nanotube; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol.
![Figure 5 MTT assay of MWNT. O-CNT, and O-CNT-PEG against HepG2 (A) and HeLa (B) cell lines.Abbreviations: Conc, concentration; MWNT, multiwalled carbon nanotube; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol.](/cms/asset/2eaa4c7a-e858-4305-8209-516d96b9652e/dijn_a_134661_f0005_c.jpg)
Figure 6 The size of tumors before and 3 days after the treatment with PTT in different groups.
Abbreviations: O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; PTT, photothermal therapy.
![Figure 6 The size of tumors before and 3 days after the treatment with PTT in different groups.Abbreviations: O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; PTT, photothermal therapy.](/cms/asset/fbca1ee7-a697-4749-b22e-424d9831cb9f/dijn_a_134661_f0006_c.jpg)
Figure 7 The stages of tumor treatment in the O-CNT-PEG group with PTT technique.
Notes: (A, C) Photograph and ultrasonography image of a cancerous mouse before the treatment, respectively. (B) Photograph of the mouse 3 days after the treatment (sonography was not feasible 3 days after the treatment).
Abbreviations: O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; PTT, photothermal therapy.
![Figure 7 The stages of tumor treatment in the O-CNT-PEG group with PTT technique.Notes: (A, C) Photograph and ultrasonography image of a cancerous mouse before the treatment, respectively. (B) Photograph of the mouse 3 days after the treatment (sonography was not feasible 3 days after the treatment).Abbreviations: O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol; PTT, photothermal therapy.](/cms/asset/c5ae038a-8297-4ba1-b38d-c853ffed892c/dijn_a_134661_f0007_c.jpg)
Table 1 Results of histopathologic evaluation
Figure 8 Malignant melanoma.
Notes: (A) (*) Histopathologic section of the laser therapy case which shows the zone of tumor necrosis (H&E). (B, C) There is the deposition of NPs (arrow) in O-CNT-PEG group within the necrotic areas (H&E). (D) Histopathologic section of the tumor in the case allocated to the O-CNT-PEG group which shows high percent of tumor necrosis (10×; (H&E)).
Abbreviations: H&E, hematoxylin and eosin; NPs, nanoparticles; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol.
![Figure 8 Malignant melanoma.Notes: (A) (*) Histopathologic section of the laser therapy case which shows the zone of tumor necrosis (H&E). (B, C) There is the deposition of NPs (arrow) in O-CNT-PEG group within the necrotic areas (H&E). (D) Histopathologic section of the tumor in the case allocated to the O-CNT-PEG group which shows high percent of tumor necrosis (10×; (H&E)).Abbreviations: H&E, hematoxylin and eosin; NPs, nanoparticles; O-CNT, oxidized carbon nanotube; PEG, polyethylene glycol.](/cms/asset/e5dfed05-34a0-4f00-974a-ce559409358f/dijn_a_134661_f0008_c.jpg)