Higher frequency of secretor phenotype in O blood group – its benefits in prevention and/or treatment of some diseases

Figures & data

Table 1 Frequency of Lewis blood group phenotype in the study population

Lewis phenotype	Secretors		Nonsecretors		Total
Le(a+b−)	0	0%	158	100%	158	20.7%
Le(a−b+)	520	100%	0	0%	520	68.3%
Le(a−b−)	60	71.4%	24	28.6%	84	11.0%
Total	580	76.1	182	23.9	762	100%

Table 2 Distribution and comparison of secretor status prevalence in men and women

Gender	Male		Female		Total		P
Secretors	368	75.6%	212	74.1%	580	76.1%	>0.05
Nonsecretors	112	24.4%	70	25.9%	182	23.9%	–
Total	480	36.0%	282	37.0%	762	100%	–

Table 3 Distribution and comparison of secretor status frequency in Rh(D)-positive and Rh(D)-negative individuals

Rhesus type	Rh-positive		Rh-negative		Total		P
Secretors	532	76%	48	77%	580	76.1%	>0.05
Nonsecretors	168	24%	14	23%	182	23.9%	–
Total	700	91.8%	62	8.1%	762	100%	–

Table 4 Frequency of secretor status in A, B, AB, and O blood group individuals

Blood group	Secretors		Nonsecretors		Total
A	171	70.1%	73	29.9%	244	32.0%
B	124	67.8%	59	32.2%	183	24.0%
AB	36	67.9%	17	32.1%	53	7.0%
O	249	88.3%	33	11.7%	282	37.0%
Total	580	75.1%	182	23.9%	762	100%

Table 5 Comparison of blood group O secretor status prevalence with A, B, and AB blood groups separately and collectively

Blood groups,	A	B	AB	A + B + AB
secretors/totals	(171/244)	(124/183)	(36/53)	(331/480)
(%)	(70.1%)	(67.8%)	(67.9%)	(69.0%)
A (171/244) (70.1%)	–	P = 0.074	P = 0.122	P = 0.065
B (124/183) (67.8%)	P = 0.074	–	P = 0.133	P = 0.071
AB (36/53) (67.9%)	P = 0.122	P = 0.133	–	P = 0.122
O (249/282) (88.3%)	P < 0.0001	P < 0.0001	P = 0.00031	P < 0.0001