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Original Research

The protective effects of cerium oxide nanoparticles against hepatic oxidative damage induced by monocrotaline

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Pages 143-149 | Published online: 17 Jan 2011

Figures & data

Figure 1 The oxidation and reduction reactions of cerium oxide (CeO2) nanoparticles.

Figure 1 The oxidation and reduction reactions of cerium oxide (CeO2) nanoparticles.

Figure 2 Nomenclatures and structures of the tumorigenic retronecine-type pyrrolizidine alkaloids.Citation13

Figure 2 Nomenclatures and structures of the tumorigenic retronecine-type pyrrolizidine alkaloids.Citation13

Table 1 Changes in hepatic cytosolic and mitochondrial GR, GSH, GST, and GPX activities in different groups

Table 2 Changes in hepatic CAT and SOD in different groups

Figure 3A 1) Regular distribution of cerium oxide (CeO2) nanoparticles intracellular in the endosomes. 2) Homogenous appearance of cytoplasm with no abnormal vaculation, original magnification ×12,500. 3) Regular distribution of CeO2 nanoparticles within normal lysosomes.

Figure 3A 1) Regular distribution of cerium oxide (CeO2) nanoparticles intracellular in the endosomes. 2) Homogenous appearance of cytoplasm with no abnormal vaculation, original magnification ×12,500. 3) Regular distribution of CeO2 nanoparticles within normal lysosomes.

Figure 3B 1) Hepatocytes organelles (mitochondria) showing normal structure. 2) Regular distribution of cerium oxide nanoparticles with homogenous size all over the cytoplasm, original magnification ×5000.

Figure 3B 1) Hepatocytes organelles (mitochondria) showing normal structure. 2) Regular distribution of cerium oxide nanoparticles with homogenous size all over the cytoplasm, original magnification ×5000.

Figure 3C 1) Even distribution of cerium oxide over the cytoplasm of the hepatocytes. 2) Normal ribosomes (rough endoplasmic reticulum), original magnification ×8000.

Figure 3C 1) Even distribution of cerium oxide over the cytoplasm of the hepatocytes. 2) Normal ribosomes (rough endoplasmic reticulum), original magnification ×8000.