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Original Research
Sustained delivery of a camptothecin prodrug – CZ48 by nanosuspensions with improved pharmacokinetics and enhanced anticancer activity
Dong Dong1 International Ocular Surface Research Center and Institute of Ophthalmology, Jinan University Medical School, Guangzhou, China;2 GuangZhou (Jinan) Biomedical Research and Development Center Co. Ltd, Guangzhou, China
, Cheng-Hui Hsiao3 Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA
, Beppino C Giovanella4 CHRISTUS Stehlin Foundation for Cancer Research, Houston, TX, USA
, Yifei Wang2 GuangZhou (Jinan) Biomedical Research and Development Center Co. Ltd, Guangzhou, China
, Diana SL Chow3 Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USACorrespondence[email protected]
& Zhijie Li1 International Ocular Surface Research Center and Institute of Ophthalmology, Jinan University Medical School, Guangzhou, ChinaCorrespondence[email protected]
Pages 3799-3817
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Published online: 24 May 2019
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