https://orcid.org/0000-0003-1063-8203
Figures & data
Figure 1 Chemical structure of nimbolide.
Figure 2 Particle size of Nim-nano before lyophilization (A) and after lyophilization (B).
Figure 3 ζ-potential of Nim-nano after lyophilization.
Figure 4 Effect of cryoprotectants on size of Nim-nano after lyophilization (means ± SD, n=3 each batch). *P<0.05 vs sucrose.
Figure 5 Release study of Nim-nano in PBS, pH 7.4 (means ± SEM, n=3 each batch).
Figure 6 In vitro cytotoxicity of Nim, Nim-nano and empty PLGA NPs (drug-free blank PLGA nanoparticles) in different cancer cells after 72 hours of incubation (means ± SEM, n=3 each batch). *P<0.05, **P<0.01, ***P<0.001 versus Nim treatment at the same dose.
Figure 7 IC50 values of Nim and Nim-nano in MCF-7, MDA-MB-231, and AsPC-1 cells after 72 hours of incubation (means ± SD, n=3 different each batch). *P<0.05.
