Figures & data
Figure 1 Schematic diagram of the coaxial electrospinning process (A) and digital pictures of the process (B).
![Figure 1 Schematic diagram of the coaxial electrospinning process (A) and digital pictures of the process (B).](/cms/asset/ab642e20-0003-4230-b455-88da5d638feb/dijn_a_27468_f0001_c.jpg)
Figure 2 Characterization of the electrospun core-sheath nanofibers. (A) FESEM images of nanofiber surfaces; (B) FESEM images of nanofiber cross-sections; (C) distribution of nanofiber diameters; (D) TEM images of the fiber core-sheath structure.
Abbreviations: FESEM, field emission scanning electron microscope; TEM, transmission electron microscopy.
![Figure 2 Characterization of the electrospun core-sheath nanofibers. (A) FESEM images of nanofiber surfaces; (B) FESEM images of nanofiber cross-sections; (C) distribution of nanofiber diameters; (D) TEM images of the fiber core-sheath structure.Abbreviations: FESEM, field emission scanning electron microscope; TEM, transmission electron microscopy.](/cms/asset/5dbbd009-6f6b-458f-aa20-ecbe4548a587/dijn_a_27468_f0002_c.jpg)
Figure 3 Differential scanning calorimetry thermograms of the components (acyclovir, PVP, SDS, and sucralose) and their core-sheath nanofibers under a heating rate of 10°C per minute and a nitrogen gas flow rate of 40 mL/minute.
Abbreviations: PVP, polyvinylpyrrolidone; SDS, sodium dodecyl sulfate.
![Figure 3 Differential scanning calorimetry thermograms of the components (acyclovir, PVP, SDS, and sucralose) and their core-sheath nanofibers under a heating rate of 10°C per minute and a nitrogen gas flow rate of 40 mL/minute.Abbreviations: PVP, polyvinylpyrrolidone; SDS, sodium dodecyl sulfate.](/cms/asset/536f1a49-92d7-4e71-8e95-55723702cfb6/dijn_a_27468_f0003_b.jpg)
Figure 4 X-ray diffraction patterns of the components (acyclovir, PVP, SDS, and sucralose) and their core-sheath nanofibers with CuKα radiation at 40 mV and 300 mA.
Abbreviations: PVP, polyvinylpyrrolidone; SDS, sodium dodecyl sulfate.
![Figure 4 X-ray diffraction patterns of the components (acyclovir, PVP, SDS, and sucralose) and their core-sheath nanofibers with CuKα radiation at 40 mV and 300 mA.Abbreviations: PVP, polyvinylpyrrolidone; SDS, sodium dodecyl sulfate.](/cms/asset/fb2a98f0-3f29-4111-b188-ab624a4de05a/dijn_a_27468_f0004_b.jpg)
Figure 5 Molecular structures of the components (A) and hydrogen bonding between acyclovir molecules and between acyclovir and PVP molecules (B).
Abbreviation: PVP, polyvinylpyrrolidone.
![Figure 5 Molecular structures of the components (A) and hydrogen bonding between acyclovir molecules and between acyclovir and PVP molecules (B).Abbreviation: PVP, polyvinylpyrrolidone.](/cms/asset/2d11b482-e161-47d7-8425-b5fcafe3278c/dijn_a_27468_f0005_c.jpg)
Figure 6 ATR-FTIR spectra of the components (acyclovir, PVP, SDS, and sucralose) and their core-sheath nanofibers at 500–4000 cm−1 and a resolution of 2 cm−1.
Abbreviations: PVP, polyvinylpyrrolidone; SDS, sodium dodecyl sulfate; ATR-FTIR, attenuated total reflectance Fourier transform infrared.
![Figure 6 ATR-FTIR spectra of the components (acyclovir, PVP, SDS, and sucralose) and their core-sheath nanofibers at 500–4000 cm−1 and a resolution of 2 cm−1.Abbreviations: PVP, polyvinylpyrrolidone; SDS, sodium dodecyl sulfate; ATR-FTIR, attenuated total reflectance Fourier transform infrared.](/cms/asset/c371381d-622c-4016-a0e5-4739828cfbbb/dijn_a_27468_f0006_b.jpg)