Figures & data
Figure 1 The emission spectra of all the light sources.
Note: Peak is the central wavelength of light sources.
Figure 2 UV-Vis absorption spectra of GNPs with different ratios of HAuCl4/BPEI (from 0.5:1 to 1:8).
Abbreviations: GNPs, gold nanoparticles; BPEI, branched polyethyleneimine.
Figure 3 Size distribution of GNPs with different ratios of HAuCl4/BPEI (from 0.5:1 to 1:8). Peak is the size of gold nanoparticles. Inset is the TEM micrograph of gold nanoparticles (1:4).
Abbreviations: BPEI, branched polyethyleneimine; GNPs, gold nanoparticles; TEM, transmission electron microscopy.
Figure 4 Zeta potential of GNPs with different ratios of HAuCl4/BPEI (from 0.5:1 to 1:8).
Abbreviations: BPEI, branched polyethyleneimine; GNPs, gold nanoparticles.
Figure 5 Zeta potential of ALA conjugated 1:4 ratio gold nanoparticles (1:4 GNPs) with different concentrations of ALA (from 0 mM to 8 mM).
Abbreviations: ALA, aminolevulinic acid; GNPs, gold nanoparticles.
Figure 6 Size distribution of ALA (from 0 mM to 8 mM) conjugated gold nanoparticles (1:4 GNPs).
Notes: Peak is the size of gold nanoparticles. Inset is the scheme of ALA-conjugated gold nanoparticles.
Abbreviations: ALA, aminolevulinic acid; GNPs, gold nanoparticles.
Figure 7 Viability of K562 cell under dark treatment.
Note: The data are representative of three duplicated experiments.
Figure 8 Viability of K562 cell after irradiation of various light sources. CCK-8 assay were performed when incubated 24 h after irradiation with (A) mercury arc lamp; (B) purple light LED; (C) green light; (D) red light LED.
Notes: Cell viability of their controls with no drug is also shown. The data are representative of three duplicated experiments.
Abbreviations: CCK-8, Cell Counting Kit 8; LED, light-emitting diode.
Figure 9 Intracellular formation of protoporphyrin IX is time-dependent.
Notes: The peak fluorescence value at 631 nm was used for kinetic measurement and an excitation of 410 nm on K562 cell incubated with GNPs, ALA and ALA-GNPs for various times.
Abbreviations: ALA, aminolevulinic acid; GNPs, gold nanoparticles.
Figure 10 Fluorescence response of SOSGR to singlet oxygen as a function of time. The irradiation treatment was performed by illuminating the samples with (A) and (B) the fluorescence spectra of green light LED; (C) and (D) the fluorescence spectra of red light LED.
Abbreviations: GNPs, gold nanoparticles; LED, light-emitting diode; SOSGR, Singlet Oxygen Sensor Green reagent.
