Safety and Efficacy of PLGA(Ag-Fe₃O₄)-Coated Dental Implants in Inhibiting Bacteria Adherence and Osteogenic Inducement under a Magnetic Field [Corrigendum]

Figures & data

Figure 1 Characterization of PLGA(Ag-Fe₃O₄).

Notes: (A) TEM image of Ag nanoparticles. (B) TEM image of Ag-Fe₃O₄ nanoparticles. (C) HRTEM image. (D) SEM image of PLGA(Ag-Fe₃O₄) covered on the planted tooth. (E) XRD. (F) FTIR spectrum. (G) Room temperature magnetic hysteresis loops of Ag-Fe₃O₄. (H) Ag-Fe₃O₄ multiple release behavior response to the magnetic field. It meant that Ag was stably bonded with Fe₃O₄.

Abbreviations: PLGA, poly (D, l-lactic-co-glycolic acid); SEI, secondary electron image; TEM, transmission electron microscopy; M, static magnetic field; emu, electromagnetic unit; H, magnetic field strength; Oe, oersted; SEM, scanning electron microscopy; XRD, X-ray powder diffraction; FTIR, Fourier transform infrared; HRTEM, high-resolution transmission electron microscopy; WD, working distance (the distance from the objective lens to focus point).

Figure 3 (A) Storage stability test result of PLGA(Ag-Fe₃O₄) nanoparticles. (B) ALP activity of osteoblasts in PBS, Fe₃O₄, or PLGA(Ag-Fe₃O₄) nanoparticles after 2, 4, and 6 days of differentiation culture; *P<0.05. **P<0.01. (C) Viability of osteoblasts incubated with different concentrations of samples for 24 hours. n=6; **P<0.01. (D) AgNOR staining in nucleoli of osteoblasts cultured with different nanoparticles. Original magnification 1,000×.

Abbreviations: M, static magnetic field; PLGA, poly (D, l-lactic-co-glycolic acid); ALP, alkaline phosphatase; AgNOR, silver staining for nucleolar organizer region.