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ORIGINAL RESEARCH

Green Synthesis and Characterization of Silver Nanoparticles Using Moringa Peregrina and Their Toxicity on MCF-7 and Caco-2 Human Cancer Cells

, , , , , , , , , & ORCID Icon show all
Pages 3891-3905 | Received 07 Dec 2023, Accepted 01 Apr 2024, Published online: 01 May 2024

Figures & data

Figure 1 Schematic diagram of biosynthesis of Moringa peregrina leaf extract mediated AgNPs and its biological activity.

Figure 1 Schematic diagram of biosynthesis of Moringa peregrina leaf extract mediated AgNPs and its biological activity.

Figure 2 FT-IR spectrum of AgNPs synthesized with M. peregrina leaf extract.

Figure 2 FT-IR spectrum of AgNPs synthesized with M. peregrina leaf extract.

Figure 3 HR-SEM image of AgNPs synthesized by M. peregrina leaf extract at different scales: (a) 10 μm and (b) 20 μm.

Figure 3 HR-SEM image of AgNPs synthesized by M. peregrina leaf extract at different scales: (a) 10 μm and (b) 20 μm.

Figure 4 EDX spectrum of AgNPs synthesized using M. peregrina leaf extract.

Figure 4 EDX spectrum of AgNPs synthesized using M. peregrina leaf extract.

Figure 5 HR-TEM image of AgNPs at different magnifications: (a and b) 50 nm and (c and d) 100 nm of synthesized using M. peregrina leaf extract.

Figure 5 HR-TEM image of AgNPs at different magnifications: (a and b) 50 nm and (c and d) 100 nm of synthesized using M. peregrina leaf extract.

Figure 6 XRD patterns of AgNPs.

Figure 6 XRD patterns of AgNPs.

Figure 7 Antioxidant potential of AgNPs using M. peregrina leaf extract. (a) ABTS free radical scavenging activity; (b) DPPH radical scavenging activity’ (c) Hydroxyl radical scavenging; (d) Superoxide radical scavenging activity; (e) Nitric oxide radical scavenging activity; (f) Reducing power of AgNP; “GAE”- Gallic acid; Values are presented as means±standard deviation.

Figure 7 Antioxidant potential of AgNPs using M. peregrina leaf extract. (a) ABTS free radical scavenging activity; (b) DPPH radical scavenging activity’ (c) Hydroxyl radical scavenging; (d) Superoxide radical scavenging activity; (e) Nitric oxide radical scavenging activity; (f) Reducing power of AgNP; “GAE”- Gallic acid; Values are presented as means±standard deviation.

Figure 8 Viability percentage of cancer cells treated with AgNPs and Doxorubicin as a positive control. (A) Nanoparticles on Caco-2; (B) Nanoparticles on MCF-7; (C) Doxorubicin on Caco-2; (D) Doxorubicin on MCF-7.

Figure 8 Viability percentage of cancer cells treated with AgNPs and Doxorubicin as a positive control. (A) Nanoparticles on Caco-2; (B) Nanoparticles on MCF-7; (C) Doxorubicin on Caco-2; (D) Doxorubicin on MCF-7.

Table 1 Anticancer Activity of AgNO3 Nano-Particles on Caco-2 and MCF-7 Cell Lines