Figures & data
Figure 1 Structural and optical characterization of mercaptosuccinic acid-coated CdTe quantum dots. (A) X-ray diffraction pattern and (B) absorption (dark line) and emission (dashed line) spectra. The emission spectrum was acquired at λ =365 nm.
Abbreviations: au, arbitrary unit; CdTe, Cadmium Telluride.
Table 1 Hemagglutination activity of Con A and UEA I, MSA-CdTe QDs, and QD-Con A and QD-UEA I conjugates
Figure 2 Mammary tissues stained by QD-Con A: normal breast (A), fibroadenoma (C), and invasive ductal carcinoma (E). Mammary tissues labeled with QD-UEA I: normal breast (B), fibroadenoma (D), and invasive ductal carcinoma (F).
Notes: Scale bar 20 μm. Tissue autofluorescence is shown in blue. QD-Con A and QD-UEA I labeling is shown in red-orange. Yellow arrows indicate ductal cells whereas asterisks indicate stromal areas. Excitation by ultraviolet light.
Abbreviations: QD-Con A, quantum dot-concanavalin A conjugate; QD-UEA I, quantum dot-Ulex europaeus agglutinin I conjugate.
Figure 3 Hematoxylin and eosin images. (A) Normal mammary tissue, (B) fibroadenoma tissue, and (C) invasive ductal carcinoma tissue. Yellow arrows indicate ductal cells while the stroma is indicated by asterisks. Scale bar 10 μm.
Figure 4 Carbohydrate-lectin inhibition assays. (A and B) Fibroadenoma samples incubated with inhibited QD-Con A and QD-UEA I conjugates, respectively. (C and D) Invasive ductal carcinoma samples incubated with inhibited QD-Con A and QD-UEA I, respectively. Scale bar 20 μm.
Abbreviations: QD-Con A, quantum dot-concanavalin A conjugate; QD-UEA I, quantum dot-Ulex europaeus agglutinin I conjugate.
