Sildenafil citrate for the management of fetal growth restriction and oligohydramnios

Figures & data

Figure 1 Doppler of umbilical artery showing an increase in systolic/diastolic ratio (3.54) at the time of diagnosis of intrauterine growth restriction and starting sildenafil citrate.

Abbreviations: PSV, peak systolic velocity; EDV, end diastolic velocity; MDV, mean diastolic velocity; TAPV, timed averaged peak velocity; S/D, systolic/diastolic ratio; PI, pulsatility index; RI, resistive index; HR, heart rate.

Figure 2 Doppler of the middle cerebral artery showing an increase in systolic/diastolic ratio (4.29) and brain-sparing effect at the time of diagnosis of intrauterine growth restriction and initiating sildenafil citrate.

Abbreviations: PSV, peak systolic velocity; EDV, end diastolic velocity; MDV, mean diastolic velocity; TAPV, timed averaged peak velocity; S/D, systolic/diastolic ratio; PI, pulsatility index; RI, resistive index; HR, heart rate.

Figure 3 Doppler of the myometrial placental junction showing a reduced flow at the time of diagnosis of intrauterine growth restriction.

Figure 4 Doppler of the myometrial placental junction showing an improvement in flow after starting sildenafil citrate.

Figure 5 Doppler of umbilical artery showing normalization of systolic/diastolic ratio (2.52) after starting sildenafil citrate.

Figure 6 Doppler of umbilical artery showing normalization of systolic/diastolic ratio (2.74) after starting sildenafil citrate.

Abbreviations: PSV, peak systolic velocity; EDV, end diastolic velocity; MDV, mean diastolic velocity; TAPV, timed averaged peak velocity; S/D, systolic/diastolic ratio; PI, pulsatility index; RI, resistive index; HR, heart rate.