A randomized clinical trial to compare levonorgestrel-releasing intrauterine system (Mirena) vs trans-cervical endometrial resection for treatment of menorrhagia

Figures & data

Table 1 Baseline characteristics (with percentages rounded for clarity)

Variable	LNG-IUS (n = 52)	TCRE (n = 52)	Pvalue
Age (years)	40.2 ± 4.3	41.5 ± 4.4	0.14
BMI (kg/m^2)	28.3 ± 4.2	26.7 ± 3.3	0.07
Duration of complaint (years)	3.35 ± 0.32	2.07 ± 0.27	0.03
Bleeding duration (day)	10.1 ± 4.2	14.5 ± 9.2	0.071*
PBAC score	595 ± 165	596 ± 185	0.069*
Menstrual interval (days)	25.6 ± 4.7	21.7 ± 6.6	0.005

Notes: Values are given as mean ± SD;

* Mann–Whitney test.

Abbreviations: BMI, body mass index; LNG-IUS, levonorgestrel intrauterine system; PBAC, pictorial blood loss assessment score; TCRE, trans-cervical resection of the endometrium.

Figure 1 Flow diagram of the trial.

Abbreviations: LNG-IUS, levonorgestrel intrauterine system; TCRE, trans-cervical resection of the endometrium.

Table 2 The satisfaction and acceptability, menstrual status and symptoms at the 12th month post-procedure follow up

	LNG-IUS (n = 45)	TCRE (n = 47)	Pvalue
Amenorrhea	5 (11.1)	21 (44.7)	<0.0001
Normal menses or hypo menorhea	31 (68.8)	24 (51.1)	0.08
No response to treat	9 (20)	2 (4.24)	0.02
Difference in bleeding score	526.8 ± 148.0	560.2 ± 177.9	0.335
Mean of satisfaction	3.08 ± 1.26	2.5 ± 1.59	0.43

Notes: Decreased number of patients is due to having no access to patients for follow up; values are given as mean ± SD or n (%).

Abbreviations: LNG-IUS, levonorgestrel intrauterine system; TCRE, trans-cervical resection of the endometrium.