Sexual behavior and infection with cervical human papillomavirus types 16 and 18

Figures & data

Table 1 Clinical and demographic data stratified by HPV type

Variables	Total (n=349)		Type 16 (n=72)		Type 18 (n=30)		Other type (n=247)
Age (mean ± SD)	44.52±9.8		42.7±9.9		46.2±8.3		44.9±9.9
24–29 years	16	(4.6)	6	(8.3)	1	(3.3)	9	(3.6)
30–54 years	271	(77.7)	55	(76.4)	25	(83.3)	191	(77.3)
≥55 years	62	(17.8)	11	(15.3)	4	(13.3)	47	(19.0)
Missing data	0
Education
Primary school	11	(4.5)	1	(2.0)	1	(4.0)	9	(5.4)
Secondary school	60	(24.6)	11	(21.6)	3	(12.0)	46	(27.4)
Bachelor	148	(60.7)	35	(68.6)	17	(68.0)	96	(57.1)
Bachelor’s degree and higher	25	(10.3)	4	(7.8)	4	(16.0)	17	(10.1)
Missing data	105
Parity
0	93	(26.7)	17	(23.6)	9	(30.0)	67	(27.1)
≥1	256	(73.3)	55	(76.4)	21	(70.0)	180	(72.9)
Missing data	0
Menopausal status
Premenopausal	246	(70.5)	53	(73.6)	20	(66.7)	173	(70.0)
Postmenopausal	103	(29.5)	19	(26.4)	10	(33.3)	74	(30.0)
Missing data	0
Smoking status
None	279	(88.0)	59	(86.8)	25	(92.6)	195	(87.8)
Smoker	6	(1.9)	1	(1.5)	0	(0.0)	5	(2.3)
Passive smoker	32	(10.1)	8	(11.8)	2	(7.4)	22	(9.9)
Missing data	32
Age of first sexual intercourse
≥30 years	31	(9.8)	7	(10.3)	3	(11.5)	21	(9.5)
20–29 years	203	(64.2)	37	(54.4)	17	(65.4)	149	(67.1)
≤19 years	82	(26.0)	24	(35.3)	6	(23.1)	52	(23.4)
Missing data	33
Number of sexual partners
≤3 partners	283	(89.6)	59	(86.8)	20	(76.9)	204	(91.9)
>3 partners	33	(10.4)	9	(13.2)	6	(23.1)	18	(8.1)
Missing data	33

Note: Data are present as number (percentage) unless stated otherwise.

Abbreviations: HPV, human papillomavirus; SD, standard deviation.

Table 2 Sexual behavior and risk of HPV16/18 infection

Variables	OR^a (95% CI)
Age of first sexual intercourse
>19 years	1.00
≤19 years	1.53 (0.90–2.61)
Number of sexual partners
≤3 partners	1.00
>3 partners	2.15 (1.03–4.48)

Note: ^aThe multivariable binary logistic regression analysis was adjusted for age, parity and smoking.

Abbreviations: HPV, human papillomavirus; OR, odds ratio; CI, confidence interval.

Table 3 Sexual behavior and risks of infection with HPV16 and HPV 18

Variables	Type 16 versus other types*				Type 18 versus other types*
	OR	(95% CI)	aOR^a	(95% CI)	OR	(95% CI)	aOR^a	(95% CI)
Age of first sexual intercourse
>19 years	1.00		1.00		1.00		1.00
≤19 years	1.78	(0.99–3.21)	1.74	(0.93–3.29)	0.98	(0.37–2.57)	0.61	(0.20–1.85)
Number of sexual partners
≤3 partners	1.00		1.00		1.00		1.00
>3 partners	1.73	(0.74–4.05)	1.32	(0.53–3.28)	3.40	(1.21–9.54)	4.58	(1.44–14.58)

Notes: ^aThe multivariable multinomial logistic regression analyses for HPV type 16 and 18 infection were adjusted for age, parity and smoking. *The category “Other types” was treated as a reference.

Abbreviations: HPV, human papillomavirus; OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval.