Effect of Delayed Cord Clamping at 30 Seconds and 1 Minute on Neonatal Hematocrit in Term Cesarean Delivery: A Randomized Trial

Figures & data

Table 1 Comparison of Maternal Characteristics Between Groups

Characteristics	DCC 30 sec (n = 79)	DCC 1 min (n = 80)	P value^β
Maternal age (yr), mean±SD	28.6±5.2	29.0±5.6	0.625
Gravida, mean±SD	2.2±1.0	2.1±0.7	0.578
Nulliparity, n (%)	23 (29.1%)	16 (20.0%)	0.299
Gestational Age (wk), mean±SD	38.9±1.1	38.8±1.2	0.304
BMI (kg/m^2), mean±SD	27.9±3.8	29.5±5.1	0.03*
Maternal Hct (%), n (%)	35.5±3.1	35.3±3.3	0.700
Anemia	6 (7.8%)	5 (6.3%)	0.738
Operation time (min), mean±SD	49.2±15.7	49.5±26.8	0.940
Cord length (cm), mean±SD	47.6±7.3	48.5±6.7	0.418
Placental weight (gm), mean±SD	551.3±102.8	569.4±109.8	0.283

Notes: ^βP value was calculated by linear regression analysis for continuous outcome and by binary regression for binary outcome. *Statistically significant difference (P value <0.05).

Abbreviations: DCC, delayed cord clamping; BMI, body mass index; Hct, hematocrit; yr, year; wk, week; SD, standard deviation.

Figure 1 Consort diagram.

Table 2 Comparison of Primary and Secondary Outcomes Between Groups

Characteristics	DCC 30 sec (Group 1) (n = 79)	DCC 1 min (Group 2) (n = 80)	Difference Between Group 2–1 (95% CI)	P value*
Neonatal Hct at 48–72hr (%), mean±SD	49.9±6.0	51.2±5.9	−1.3 (−3.16 to 0.56)	0.169
Neonatal anemia n (%)	14 (17.7%)	8 (10.0%)	−7.7% (−18.4 to 3.0)	0.159
Polycythemia n (%)	0 (0)	0 (0)	NA	NA
Mb at 48–72hr, mean±SD	9.4±1.9	9.2±2.3	0.13 (−0.52 to 0.79)	0.692
Clinical jaundice, n (%)	19 (24.1%)	17 (21.3%)	−2.8% (−15.8 to 10.2)	0.673
Phototherapy n (%)	15 (19.0%)	11 (13.8%)	−5.2% (−16.7 to 6.2)	0.372
Estimate blood loss (mL), mean±SD	274.7±110.3	272.5±97.1	2.2 (−30.4 to 34.7)	0.895

Note: *P value was calculated by linear regression analysis for continuous outcome and by binary regression for binary outcome.

Abbreviations: DCC, delay clamp cord; CI, confidence interval; SD, standard deviation; Hct, hematocrit; Mb, microbilirubin.

Table 3 Comparison of Neonatal Outcomes Between Groups

Characteristics	DCC 30 sec (n = 79)	DCC 1 min (n = 80)	P value*
Newborn birthweight (kg), mean±SD	3124.9±359.3	3212.7±395.9	0.146
Newborn length (cm), mean±SD	50.5±1.8	50.2±2.3	0.505
Newborn HC, mean±SD	33.5±1.2	33.6±2.9	0.709
Apgar 1 min, mean±SD	9.1±0.5	9.1±0.6	0.654
Apgar 5 min, mean±SD	10.0±0.2	9.9±0.3	0.154
Apgar 10 min, mean±SD	10.0±0.2	10.0±0.2	0.413
Respiratory complication, n (%)	3 (3.8%)	1 (1.3%)	0.305
NICU admission, n (%)	1 (1.3)	0 (0)	NA

Notes: *P value was calculated by linear regression analysis for continuous outcome and by binary regression for binary outcome. Respiratory complications included respiratory distress syndrome, pneumonia and transient tachypnea of the newborn.

Abbreviations: SD, standard deviation; DCC, delay clamp cord; HC, head circumference; NICU, neonatal intensive care unit.