The Impact of Spinal Anesthesia and Use of Oxytocin on Fluid Absorption in Patients Undergoing Operative Hysteroscopy: Results from a Prospective Controlled Study

Figures & data

Table 1 Mean BMI, Uterine Size, and Endometrial Thickness (ET)

	General Anesthesia			Spinal Anesthesia
	Mean ± S.D.	S.E.	C.I.	Mean ± S.D.	S.E.	C.I.
Resection of endometrial polyp	(11)			(4)
Mean BMI	29.6 ± 4.0	1.1	27.3–31.9	33.0 ± 13.5	6.7	11.6–54.4
Mean uterine size (weeks)	7.4 ± 1.2	0.3	6.7–8.0	9.7 ± 1.5	0.9	5.9–13.5
Mean ET (mm)	10.3 ± 2.2	0.6	9.0–11.6	13.8 ± 2.6	1.3	9.6–17.9
Hysteroscopic myomectomy	(26)			(6)
Mean BMI	29.4 ± 4.6	0.9	27.5–31.2	29.8 ± 5.2	2.1	24.3–35.3
Mean uterine size (weeks)	9.5 ± 2.1	0.4	8.7–10.4	9.7 ± 1.5	0.6	8.1–11.2
Mean ET (mm)	10.5 ± 3.0	0.6	9.2–11.7	11.7 ± 0.8	0.3	10.8–12.5
TCRE	(11)			(14)
Mean BMI	29.8 ± 5.8	1.7	25.9–33.7	27.2 ± 6.7	1.8	23.3–31.0
Mean uterine size (weeks)	9.4 ± 1.7	0.5	8.3–10.5	10.4 ± 1.7	0.5	9.4–11.4
Mean ET (mm)	10.2 ± 3.3	1	8.0–12.4	14.0 ± 3.3	0.9	12.1–15.9
Resection of septum	(11)			(2)
Mean BMI	29.1 ± 3.6	1.1	26.6–31.5	20.5 ± 0.7	0.5	14.1–26.9
Mean uterine size (weeks)	6.5 ± 0.7	0.2	6.0–6.9	8.5 ± 2.1	1.5	10.6–27.6
Mean ET (mm)	9.3 ± 1.8	0.5	8.1–10.5	12.0 ± 2.8	2	13.4–37.4

Notes: S.D. = standard deviation, S.E. = standard error, C.I. = confidence interval.

Abbreviations: BMI, body mass index; ET, endometrial thickness.

Table 2 Mean Arterial Blood Pressure (MAP), Duration of Surgery, Estimated Blood Loss (EBL), and Size of Polyp/Fibroid Lesions

	General Anesthesia			Spinal Anesthesia			p-value
	Mean ± S.D.	S.E.	C.I.	Mean ± S.D.	S.E.	C.I.
Resection of endometrial polyp	(11)			(4)
MAP	81.0 ± 15.0	4.0	72.3–89.7	88.3 ± 6.1	3.0	78.6–97.9	0.174
Duration of surgery (min)	36.4 ± 20.5	5.5	24.6–48.3	37.5 ± 8.7	4.3	23.7–51.3	0.880
EBL (cc)	59.3 ± 33.8	33.8	39.7–78.8	60.0 ± 46.2	23.1	13.5–133.5	0.973
Size of polyp (cm)	2.7 ± 0.9	0.2	2.1–3.2	3 ± 0.8	0.4	1.7–4.3	0.543
Hysteroscopic myomectomy	(26)			(6)
MAP	82.3 ± 10.8	2.1	77.9–86.7	83 ± 5.7	2.3	77.0–90.0	0.829
Duration of surgery (min)	43.8 ± 22.9	4.5	34.6–53.1	39.2 ± 12.0	4.9	26.6–51.7	0.492
EBL (cc)	83.8 ± 57.9	11.4	60.5–107.2	61.7 ± 69.1	28.2	10.9–134.2	0.490
Size of fibroid (cm)	4.4 ± 1.9	0.4	3.6–5.2	3.2 ± 1.5	0.6	1.6–4.7	0.110
TCRE	(11)			(14)
MAP	87.0 ± 10.0	3.0	80.3–93.7	87.8 ± 12.7	3.4	80.5–95.1	0.868
Duration of surgery (min)	34.5 ± 11.3	3.4	27.0–42.1	51.1 ± 12.9	3.4	43.6–58.5	0.003
EBL (cc)	47.3 ± 9.0	2.7	41.2–53.3	64.3 ± 50.8	13.6	35.0–93.6	0.239
Resection of septum	(11)			(2)
MAP	82.5 ± 8.0	2.4	77.2–87.9	75.0 ± 2.8	2.0	49.6–100.4	0.061
Duration of surgery (min)	49.5 ± 23.3	7.0	33.9–65.2	40.0 ± 0	0	40–40	0.204
EBL (cc)	71.8 ± 51.5	15.5	37.2–106.4	65.0 ± 49.5	35.0	379.7–509.7	0.866

Notes: S.D. = standard deviation, S.E. = standard error, C.I. = confidence interval. The size of fibroids was measured by consultant gynecologist using a high-resolution transvaginal ultrasound.

Abbreviations: MAP, mean arterial blood pressure; EBL, estimated blood loss; TCRE, trans-cervical resection of the endometrium.

Table 3 Number of Surgeries and Mean Fluid Deficit per Type of Surgery

	General Anesthesia			Spinal Anesthesia			p-value
	Mean ± S.D.	S.E.	C.I.	Mean ± S.D.	S.E.	C.I.
Resection of Endometrial Polyp
Number of cases	14			4
Mean fluid deficit (cc)	392 ± 178	54	272–511	220 ± 36	18	163–276	0.010
Hysteroscopic Myomectomy
Number of cases	26			6
Mean fluid deficit (cc)	564 ± 371	74	411–717	308 ± 66	27	239–378	0.003
TCRE
Number of cases	11			14
Mean fluid deficit (cc)	790 ± 318	100	563–1017	229 ± 75	20	185–272	< 0.001
Resection of Septum
Number of cases	11			2
Mean fluid deficit (cc)	781 ± 429	129	494–1070	1000 ± 1131	800	9165–11,165	0.833

Notes: S.D. = standard deviation, S.E. = standard error, C.I. = confidence interval.

Abbreviation: TCRE, trans-cervical resection of the endometrium.