Risk Factors Associated with Preterm Delivery in Singleton Pregnancy in a Tertiary Care Hospital in South India: A Case Control Study

Figures & data

Table 1 Association of Risk Factors of Preterm Birth

Risk Factor	Group	Case		Control		OR	P- value
		Number	Percentage	Number	Percentage
Pregnancy induced hypertension	YES	37	19.4	4	2	11.77	<0.001
	NO	154	80	196	98
Amniotic fluid volume	NORMAL	156	81.7	196	98	10.99	<0.001
	ABNORMAL	35	18.3	4	2
Premature rupture of membranes	YES	48	25.1	11	5.5	5.76	<0.001
	NO	143	74.9	189	94.5
History of previous preterm delivery	YES	17	8.9	4	2	4.78	0.003
	NO	174	91.1	196	98
Other systemic diseases	YES	36	18.8	10	5	4.41	<0.001
	NO	155	81.2	190	95
Urinary tract infection	YES	23	12	7	3.5	3.77	0.002
	NO	168	88	193	96.5
Anaemia	YES	39	20.4	20	10	2.31	0.004
	NO	152	96.6	180	90
Gestational diabetes mellitus	YES	33	17.3	20	10	1.88	0.039
	NO	158	82.7	180	90
Area of residence	Rural	62	32.5	54	27	0.77	0.268
	Urban	129	67.5	146	73
Parity	PRIMI	77	40.3	89	44.5	1.18	0.415
	MULTI	114	59.7	111	55.5
Infertility	YES	23	12.0	23	11.5	1.05	0.877
	NO	168	88	177	88.5
History of abortion	YES	47	24.6	35	17.5	1.54	0.106
	NO	144	75.4	165	82.5
Hypothyroid	YES	33	17.3	21	10.5	1.78	0.057
	NO	158	82.7	179	89.5
Placenta	NORMAL	186	97.4	199	99.5	5.35	0.197
	ABNORMAL	5	2.6	1	0.5
Vaginal infection	YES	7	3.7	4	2	1.86	0.371
	NO	184	96.3	196	98
Other infection	YES	15	7.9	11	5.5	1.46	0.419
	NO	176	92.1	189	94.5

Table 2 Independent Risk Factors of Preterm Birth

Risk Factors	Multivariate OR	95% CI	P value
Pregnancy induced hypertension	14.61	4.838–44.105	<0.001
Amniotic fluid volume	10.67	3.458–32.979	<0.001
Premature rupture of membrane	10.27	4.824–21.859	<0.001
History of previous preterm delivery	4.12	1.224–13.853	0.002
Urinary tract infection	3.67	1.390–9.682	0.002
Other systemic diseases	2.78	1.28–6.395	<0.001
Anaemia	2.54	1.281–5.026	0.004

Table 3 Collinearity Statistics

Model	Collinearity Statistics
	Tolerance	VIF
AGE	0.866	1.154
PREMAT RUP	0.965	1.037
H/O ABORTION	0.939	1.065
PIH	0.907	1.102
GDM	0.902	1.108
HYPT	0.965	1.036
ANAEMIA	0.981	1.019
H/O PRETM	0.932	1.072
AF VOL	0.944	1.059
UTI	0.965	1.036
Other disease	0.914	1.094
MODE OF DELIVERY	0.881	1.135