Double Balloon Combined with Oxytocin in Labor Induction: Analysis of Multivariate Factors Affecting the Efficacy of Cervical Ripening

Figures & data

Table 1 Univariate Analysis of Relevant Factors in the Vaginal Delivery Group and Cesarean Section Group of Patients

Items	Vaginal Delivery Group (n = 180)	Cesarean Section Group (n = 50)	t/χ^2 value	P value
Age (years, x±s)	29.91±4.51	29.60±3.66	0.448	0.654
Body height (cm, x±s)	159.01±5.6 2	159.71±7.71	1.423	0.159
Pre-pregnancy BMI (kg/m^2, x±s)	21.68±2.81	21.93±2.93	−0.545	0.586
Post-pregnancy BMI (kg/m^2, x±s)	27.51±2.85	28.23±3.18	−1.543	0.124
Gravidity (times, x±s)	2.17±1.35	1.62±0.95	3.302	<0.001
Gestational weeks for labor induction (weeks, x±s)	39.68±1.23	39.88±1.04	−1.083	0.280
Cervical score (points, x±s)	4.95±0.21	4.90±0.30	1.220	0.227
Prenatal anxiety (n)	24	23	25.682	<0.001
Neonatal weight (g, x±s)	3292.66±446.87	3398.60±412.78	−1.507	0.133
Amniotic fluid index (n)			1.982	0.159
≤50 mm	11	6
50–250 mm	169	44
Complication (n)
Pregnancy-induced hypertension	20	3	1.136	0.287
Gestational diabetes	68	16	0.563	0.453
Acute chorioamnionitis	5	27	85.718	<0.001
Fetal distress	13	32	80.157	<0.001
Reason for balloon removal (n)
Placement of cervical ripening balloon for >12h	74	34	11.359	<0.001
Spontaneous balloon shedding	64	11	3.272	0.070
Regular contractions for delivery	32	12	0.979	0.322
Premature rupture of membranes	9	1	0.847	0.357

Abbreviation: BMI, body mass index.

Table 2 Variable Grouping and Coding

Variables	Grouping	Coding
Prenatal anxiety	With	1
	Without	2
Acute chorioamnionitis	With	1
	Without	2
Fetal distress	With	1
	Without	2
Placement of cervical ripening balloon for >12h	With	1
	Without	2
Gravidity	Original value input

Table 3 Logistic Regression Analysis of Suspicious Factors for the Success of Cervical Ripening Balloon Combined and Oxytocin for Labor Induction

Influencing Factors	S.E	Wald χ^2	P value	OR	OR (95% CI)
With prenatal anxiety	1.231	1.982	0.159	1.796	0.575–3.123
With Acute chorioamnionitis	1.412	7.208	0.001	1.456	1.257–2.112
With fetal distress	1.113	7.763	0.001	1.371	1.331–2.633
Placement of cervical ripening balloon for >12h	1.145	7.423	0.001	1.563	1.231–3.263
Multi-gravidity	0.142	9.089	0.001	0.736	0.455–0.875

Abbreviations: OR, odds ratio; CI, confidence interval.

Table 4 The Predictive Value of Various Indicators for the Failure of Cervical Ripening Balloon Combined with Oxytocin for Labor Induction

Items	AUC	95% CI	Sensitivity (%)	Specificity (%)
Acute chorioamnionitis	0.856	0.719–0.924	80.61	81.70
Fetal distress	0.789	0.702–0.814	81.44	83.48
Placement of cervical ripening balloon for >12h	0.861	0.725–0.938	82.01	73.82
Gravidity	0.712	0.679–0.811	83.49	84.57
Joint prediction	0.931	0.714–0.811	91.24	90.73

Abbreviations: AUC, area under the curve; CI, confidence interval.

Data Sharing Statement

All data generated or analyzed during this study are included in this published article.