Clinical Profile of COVID-19 Patients Presenting with Uveitis – A Short Case Series

Figures & data

Table 1 Systemic Symptoms, Ocular Findings, Classification of Uveitis and Given Medication

Demographic Data	Case 1	Case 2	Case 3
Age (year)	19	29	62
Gender	Male	Male	Male
Eye and systemic symptoms
Redness	Both eyes	Both eyes	Right eye
Photophobia	Both eyes	Both eyes	No
Blurred vision	Both eyes	Both eyes	Right eye
Lacrimation	Both eyes	Both eyes	No
Loss of taste and or smell	Yes	Yes	No
Fatigue	Yes	Yes	No
Fever	41°C	40°C	36.5°C
Classification of uveitis	Bilateral anterior uveitis	Bilateral intermediate and posterior uveitis	Right eye iridocyclitis
Medication	Topical and systemic steroid	Topical and systemic steroid	Topical steroids
	Cyclopentolate	Cyclopentolate	Cyclopentolate

Table 2 Relevant Laboratory Tests

Laboratory Tests	Case 1	Case 2	Case 3	Normal Values
SARS-CoV-2 RT-PCR	Positive	ND	Positive
Leucocytes	13.2	7.8	6	4000–10,000/μL
ESR	47	5	12	0–20 mm/h
CRP	55	7	4	Less than 10 mg/L
RF	5	6	3	Less than 14 IU/mL
ALT	14	20	22	7–55 U/L
AST	18	22	28	8–48 U/L
Creatinine	1.1	1	1.1	0.9 to 1.3 mg/dL
ANA	Negative	Negative	Negative	7–55 U/L
ACE	10	18	12	Less than 40 nmol/mL/min
HLA B27	Negative	Negative	Negative
Brucella	Negative	Negative	Negative
PPD	Negative	Negative	Negative
TPHA	ND	Titer <1:80	ND	Titer <1:80
HIV test	Negative	Negative	Negative

Note: *ND: Not done.

Abbreviations: ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; RF, rheumatoid factor; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ANA, antinuclear antibody; ACE, angiotensin converting enzyme; HLB27, human leukocyte antigen B27; PPD, purified protein derivative; TPHA, treponema pallidum hemagglutination; HIV, human immunodeficiency virus; ND, not done.

Figure 1 Color fundus in right (A) and left (B) eyes of 29‐year‐old male COVID-19 patient demonstrating (A) vascular sheathing indicating vasculitis (B) RE web like vitreous veils indicating intermediate uveitis.

Figure 2 Slit‐lamp examination eyes of 62‐year‐old male COVID-19 patient demonstrating endothelial keratic precipitate (white arrow), cells in the anterior chamber indicating iridocyclitis (yellow arrows).