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Case Report

Granulomatous Reaction to Dermal Injection of Growth Factors from Umbilical Cord Blood-Derived Mesenchymal Stem Cells: A Case Report

ORCID Icon, , , , &
Pages 719-723 | Published online: 05 Oct 2021

Figures & data

Figure 1 Clinical characteristics of the patient. Granulomas presented in the patient as multiple yellowish papuloplaques distributed in a grid pattern on the anterior of the neck were found at all injection sites. (A left view, B front view, C right view).

Figure 1 Clinical characteristics of the patient. Granulomas presented in the patient as multiple yellowish papuloplaques distributed in a grid pattern on the anterior of the neck were found at all injection sites. (A left view, B front view, C right view).

Figure 2 Histopathological characteristics of the patient. Dermal granuloma was found on histological examination of lesional skin with a well-demarcating feature. Macrophages and multi-nucleated giant cells were found along the periphery of the granuloma. (A hematoxylin-eosin, ×40, B hematoxylin-eosin, ×200).

Figure 2 Histopathological characteristics of the patient. Dermal granuloma was found on histological examination of lesional skin with a well-demarcating feature. Macrophages and multi-nucleated giant cells were found along the periphery of the granuloma. (A hematoxylin-eosin, ×40, B hematoxylin-eosin, ×200).

Figure 3 Immunohistochemistry of the patient. The granuloma of the patient was not immunohistochemically stained with PAS or Alcian blue, revealing no fungal infection or mucin deposition. (A PAS, ×100, B Alcian blue, ×100).

Figure 3 Immunohistochemistry of the patient. The granuloma of the patient was not immunohistochemically stained with PAS or Alcian blue, revealing no fungal infection or mucin deposition. (A PAS, ×100, B Alcian blue, ×100).