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International Medical Case Reports Journal Volume 16, 2023 - Issue
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Case reports

Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction

Zekewos Demissie1 Department of Internal Medicine, Lancet General Hospital, Addis Ababa, EthiopiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6810-6619View further author information
ORCID Icon,
Nahom Zemedkun1 Department of Internal Medicine, Lancet General Hospital, Addis Ababa, EthiopiaORCID Iconhttps://orcid.org/0009-0006-8663-3096View further author information
ORCID Icon,
Abraham Demile1 Department of Internal Medicine, Lancet General Hospital, Addis Ababa, EthiopiaView further author information
,
Berhanu Nega2 Department of Surgery, Division of Cardiothoracic Surgery, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaView further author information
,
Yonas Bekuretsion3 Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaView further author information
,
Bisrat Getachew4 Department of Otolaryngology, Head and Neck Surgery, St. Paul Millennium Medical College, Addis Ababa, EthiopiaView further author information
&
Bethelhem Berhanu5 Department of Radiology, St. Paul Millennium Medical College, Addis Ababa, EthiopiaView further author information
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Pages 757-761 | Received 02 Sep 2023, Accepted 11 Nov 2023, Published online: 16 Nov 2023

Figures & data

Figure 1 Coronal and axial neck and chest CT scan shows asymmetric nodular thickening of the upper thoracic trachea (blue arrow) with a luminal narrowing >50% (A and B). Axial neck and chest CT scan shows asymmetric soft-tissue thickening of the intrathoracic trachea (yellow arrow) with significant airway narrowing (C).

Figure 1 Coronal and axial neck and chest CT scan shows asymmetric nodular thickening of the upper thoracic trachea (blue arrow) with a luminal narrowing >50% (A and B). Axial neck and chest CT scan shows asymmetric soft-tissue thickening of the intrathoracic trachea (yellow arrow) with significant airway narrowing (C).

Figure 2 Vocal cord (green arrow) (A). Suprastomal granulation tissue (blue arrow) (B and C). Friable mass with ragged mucosa over the anterior and anterolateral part of the trachea around supracarinal area occluding ~60% of the lumen (yellow arrow) (D).

Figure 2 Vocal cord (green arrow) (A). Suprastomal granulation tissue (blue arrow) (B and C). Friable mass with ragged mucosa over the anterior and anterolateral part of the trachea around supracarinal area occluding ~60% of the lumen (yellow arrow) (D).

Figure 3 Section of tracheal sample showing acanthotic squamous epithelium with subepithelial deposition of pink hyaline extracellular material. Congo red stain was positive.

Figure 3 Section of tracheal sample showing acanthotic squamous epithelium with subepithelial deposition of pink hyaline extracellular material. Congo red stain was positive.

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