Multidisciplinary Management of Oral Manifestations in Pregnant Women with Beta-Thalassemia Major: A Case Report

Figures & data

Table 1 First and Last Visit Laboratory Test Results

Hematology Parameters	First Visit	Last Visit	Normal Range
Hemoglobin (Hb)	9.7 g/dl (L)	10.3 g/dL (L)	12.3–15.3 g/dL
Hematocrit (Ht)	30.2% (L)	32.0% (L)	36.0–45.0%
Erythrocytes	6.27 million/mL (H)	4.92 million/mL (N)	4.5–5.1 million/mL
MCV	74.9 fl (L)	81.2 fl (N)	80–96 fl
MCH	22.7 pg (L)	26.3pg (L)	27.5–33.2 pg
MCHC	30.3% (L)	32.2% (L)	33.4–35.5%
Leukocytes	14.11×10^3/uL (H)	5.4×10^3/uL (N)	4.4–11.3×10^3/uL
Lymphocyte	8% (L)	23% (N)	18–44%
Monocyte	10% (H)	5% (N)	2–8%
Platelets	720 ×10^3/uL (H)	514×10^3/uL (H)	150–450×10^3/uL
Serum Ferritin	3989.5 ng/mL (H)	3006.9 ng/mL (H)	15–150 ng/mL

Abbreviations: MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; L, low; N, normal; H, high.

Figure 1 (A–G) Intraoral clinical feature at the first visit. The appeared gingival hyperplasia, erythema, soft consistency, a dark red, rounded gingival margin, and tendencies to bleed on the labial, buccal, palatal, and lingual regions.

Figure 2 (A–F) The first follow-up visit. (G–M) The second follow-up visit. There has been no clinical change in the gingiva.

Figure 3 (A) The follow-up visit was nine days after the initial visit. (B) The follow-up visit was one month after the initial visit. (C) The follow-up visit was one week after the 4th visit. Gingival enlargement decreased in all regions.

Figure 4 (A) The follow-up visit was two months from the initial visit. Gingival enlargement resolved in the anterior and posterior regions of the maxilla and mandible. (B) The follow-up visit was two weeks after the 6th visit. Gingival enlargement of all regions of the maxilla and mandible resolved, except for the palatal-anterior part of the maxilla. (C) The follow-up visit was three months of therapy after the initial visit, which showed significant improvement in the gingiva.

Figure 5 Summary of the multidisciplinary management.