Immunoglobulin-E (IgE) Screening for Detecting Mouthwash Allergic Reactions with Recurrent Oral Erythema Multiforme: A Case Report

Figures & data

Figure 1 Oedema of the upper and lower lip with hemorrhagic crusts and bleeding easily (A); Multiple irregular ulcer lesions surrounded by erythema areas: Upper labial mucosa (B); Lower labial mucosa (C); Left buccal mucosa (D); Right buccal mucosa (E); Tongue dorsum (F); Right lateral tongue (G); Left lateral tongue (H); Tongue ventral (I); and Floor of the mouth (J).

Table 1 Hematology Examination Result

Parameter	Result	Reference	Value
Complete Blood Count
Hemoglobin	11.0^L	12.0–15.0	g/dL
White Blood Cell Count	9.39	3.60–10.60	x 10^3/µL
Red Blood Cell Count	4.14	3.80–5.20	10^6/µL
Hematocrit*	34.20^L	35–49	%
Platelet Count	362	150–450	x 10^3/µL
MCV	82.6	80–100	fL
MCH	27	26–34	pg
MCHC	32	32–36	g/dL
Basophil	0	0–2	%
Eosinophil	0^L	1–3	%
Abs. Neutrophil	0	2–6	%
Neutrophil	85	50.0–70.0	%
Lymphocyte	12	18–42	%
Monocyte	3	2–11	%
Immunology
Total IgE	612^H	< 100	IU/mL
TORCH
Anti HSV-1 IgG	5.73	Non-reactive: < 9	U/mL
		Grayzone: 9–11
		Reactive: > 11

Abbreviations: L, low; H, high; MCV, Mean corpuscular volume; MCH, Mean corpuscular hemoglobin; MCHC, Mean corpuscular hemoglobin concentration; IgE, Immunoglobulin-E; HSV, Herpes simplex virus; IgG, Immunoglobulin-G.

Figure 2 Improvement of the oral lesion on the twelfth day: Lips (A); Upper labial mucosa (B); Lower labial mucosa (C); Left buccal mucosa (D); Right buccal mucosa (E); Tongue dorsum (F); Right lateral tongue (G); Left lateral tongue (H); Tongue ventral (I); and Floor of the mouth (J).

Table 2 Total IgE Serum Level Examination

	1st visit	2nd visit	Reference	Value
Total IgE	612^H	385^H	< 100	IU/mL

Abbreviations: H, high; IgE, Immunoglobulin-E.