N-acetylcysteine overdose after acetaminophen poisoning

Figures & data

Table 1 Trends of cell blood count, and renal and liver function tests

Cell blood count/days	1	2	3	4	5	6	7	8	9	10	11	12
White blood cells ×1,000	33.7	18	10.1	12.9	8.6	9.1	9.5	10.3	11	11	14	10
Red blood cells (mil/mic)	3.79	1.3	2.2	3.01	2.42	2.26	3.93	5.06	4.4	3.5	3	2.55
Hemoglobin (mg/dL)	12.6	4.5	7.5	8.9	7.9	8.1	12.2	15.8	14	9.7	7.7	7.8
Hematocrit (%)	35.9	13	20.5	26.7	21.5	23.9	35.5	46.1	39	55	28	23.6
Platelets ×1,000	70	29	63	20	43	36	43	169	54	34	22	73
Renal function
Urea (mg/dL)	62	55	143	101	87.9	140	152	155	175	234	260	323
Creatinine (mg/dL)	1.98	3.8	5.1	5.8	4.49	5.7	3.9	3.81	4.5	5.7	5.1	5.87
Sodium (mEq/L)	152	146	145	147	–	151	130	146	153	153	151	148
Potassium (mEq/L)	3.78	3.5	3.45	3.2	–	3.3	3.5	3.22	3.5	3.2	3.5	4
Blood glucose	121	140	139	–	–	–	–	–	–	140	–	–
Liver function
SGOT (U/L)	576	689	672	481	339	162	128	77	55	39	46	46
SGPT (U/L)	437	506	480	349	221	132	110	92	65	47	45	45
ALKP (U/L)
PTindex	19	15	16.5	13.2	–	12.9	12.9	13	14	14	13	13.2
INR	1.2	1.6	1.83	1.1	–	1.2	1.2	1	1.2	1.1	1	1.21
PTT (seconds)	2.3	60	50.8	35	–	27.6	31	37.5	29	33	36	37.1
Bilirubin total (mg/dL)	1.22	1.2	1.29	1.31	–	1.6	1.15	1.28	1.1	1	1.1	1.08
Bilirubin direct (mg/dL)	0.3	0.4	0.4	0.5	–	0.5	–	0.6	–	–	–	–

Abbreviations: INR, international normalized ratio; PTT, partial thromboplastin time; PT, prothrombin time; ALKP, alkaline phosphatase; SGOT, serum glutamic oxaloacetic transaminase; SPGT, serum glutamic pyruvic transaminase.