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International Medical Case Reports Journal Volume 9, 2016 - Issue
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Case-Report

Malignant melanoma of the nasal septum, a rare tumor, occurring in a 54-year-old patient after hereditary retinoblastoma treatment

Windinmanégdé Pierre Djiguimdé1 Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina FasoCorrespondence[email protected]
,
Ibrahim Abib Diomandé2 Ophthalmology Department, University Hospital of Bouaké, University Alassane Ouattara, Bouaké, Cote d’Ivoire
,
Nicolas Bonnin3 Ophthalmology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France
,
Nicolas Saroul4 Otorhinolaryngology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France
,
Abdoulaye Touré5 Radiology Department, University Hospital of Yopougon, University Félix Houphouët Boigny, Abidjan, Côte d’Ivoire
,
Jérôme Sanou1 Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso
,
Paté Sankara1 Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso
,
Marc Russier4 Otorhinolaryngology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France
,
Laurent Gilain4 Otorhinolaryngology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France
,
Ahgbatouhabéba Ahnoux-Zabsonré1 Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso
,
Nonfounikoun Meda1 Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso
&
Franck Bacin3 Ophthalmology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France
 show all
Pages 25-28 | Published online: 09 Feb 2016

Figures & data

Figure 1 Preoperative CT scan showing the nasal tumor.

Notes: (A) Axial computed tomography scan of sinus with a parenchymal opening; (B) coronal bone with an opening showing a thickening tissue of the right nasal cavity.
Figure 1 Preoperative CT scan showing the nasal tumor.

Figure 2 Infiltration of the right nasal cavity wall with a melanoma arriving in depth to the cartilage without invading it.

Notes: Hematoxylin-eosin-saffron staining (magnification × 2). Image courtesy of JL Kemeny.
Abbreviation: hematoxylin-eosin-saffron.
Figure 2 Infiltration of the right nasal cavity wall with a melanoma arriving in depth to the cartilage without invading it.

Figure 3 Detail of tumor melanoma cells that have an atypical nucleus. Note: Image courtesy of JL Kemeny.

Figure 3 Detail of tumor melanoma cells that have an atypical nucleus. Note: Image courtesy of JL Kemeny.

Figure 4 Brown marking of intracytoplasmic tumor cells with HMB45 and melan A in immunohistochemistry on paraffin section (magnification ×40).

Note: Image courtesy of JL Kemeny.
Figure 4 Brown marking of intracytoplasmic tumor cells with HMB45 and melan A in immunohistochemistry on paraffin section (magnification ×40).

Figure 5 Postoperative computed tomography showing empty nasal cavities.

Figure 5 Postoperative computed tomography showing empty nasal cavities.

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