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Case Report

Epstein–Barr virus-associated iris smooth muscle tumor with epithelioid morphology in AIDS patients: a case report

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Pages 83-86 | Published online: 30 Mar 2016

Figures & data

Figure 1 A well-circumscribed amelanotic iris mass with underlying multiple posterior pigment epithelial cysts.

Figure 1 A well-circumscribed amelanotic iris mass with underlying multiple posterior pigment epithelial cysts.

Figure 2 UBM revealed a hypoechoic mass coalesced with iris stroma with 5.6 mm horizontal diameter and 9.3 mm vertical diameter.

Abbreviation: UBM, ultrasound biomicroscopy.
Figure 2 UBM revealed a hypoechoic mass coalesced with iris stroma with 5.6 mm horizontal diameter and 9.3 mm vertical diameter.

Figure 3 Histopathology and Immunohistochemical stain.

Notes: (A) Histopathology of the surgical specimen showing attached iridic tissue (H&E ×40). (B) Tumor cells having plump shape and epithelioid appearance with mildly pleomorphic and vesicular nuclei (H&E ×400). (C) Immunohistochemical stain for alpha smooth muscle actin (IHC ×100). (D) In situ hybridization for EBER shows positive reaction (EBER ×400).
Abbreviations: EBER, Epstein–Barr virus-encoded RNA; H&E, hematoxylin and eosin; IHC, immunohistochemistry.
Figure 3 Histopathology and Immunohistochemical stain.

Figure 4 Final slit-lamp biomicroscopy at 8 months revealed the absence of tumor recurrence.

Figure 4 Final slit-lamp biomicroscopy at 8 months revealed the absence of tumor recurrence.