Evaluation of Potential Drug Interactions with AiDKlinik^® in a Random Population Sample

Figures & data

Figure 1 Flow chart of subjects selected for inclusion into the study.

Table 1 Characteristics of the Analysed Study Population (n=264)

Characteristic	Frequency (%)	Mean ± SD
Gender
Male	129 (48.86%)
Female	135 (51.13%)
Age		62.90 ± 10.45
<40 years	8 (3.03%)
40–50 years	24 (9.09%)
51–60 years	65 (24.62%)
61–70 years	90 (34.09%)
>70 years	77 (29.17%)
Body Mass Index (BMI)		29.35 ± 5.22
BMI < 20	43 (16.29%)
BMI 20–25	126 (47.73%)
BMI > 25	95 (35.98%)
Interactions		1.60 ± 1.21
No interaction	182 (68.94%)
1–2 interactions	72 (27.28%)
3–4 interactions	8 (3.03%)
≥5 interactions	2 (0.76%)

Abbreviations: BMI, body-mass-index; %, percent; SD, standard deviation.

Figure 2 Gender distribution in the different age groups.

Table 2 Drug Interactions in Germany (n=264) in a Random Sample Population Stratified by Gender and Non-Prescription and as Needed Medications

	Frequency (%)
Sex	No drug interaction (n=182)	Drug interaction (n=82)	χ^2-Value	p value
Male (n=129)	90 (69.77%)	39 (30.23%)	0.081	p=0.776
Female (n=135)	92 (68.15%)	43 (31.85%)
	No as-needed medication (n=186)	As-needed medication (n=78)	χ^2-Value	p value
Male (n=129)	97 (75.19%)	32 (24.81%)	2.722	p=0.099
Female (n=135)	89 (65.93%)	46 (34.07%)
	Self-medication (n=165)	No self-medication (n=99)	χ^2-Value	p value
Male (n=129)	67 (51.94%)	62 (48.06%)	12.007	p=0.0005
Female (n=135)	98 (72.59%)	37 (27.41%)

Abbreviations: %, percent; n, sample size.

Table 3 Drug Interactions in a Random Sample Population in Germany (n=264), Stratified by Age

		Frequency (%)
Age Group	Total (n=264)	No Interaction (n=182)	Interaction (n=82)
< 40 years	8 (3.03%)	4 (2.20%)	4 (4.88%)
40–50 years	24 (9.09%)	17 (9.34%)	7 (8.54%)
51–60 years	65 (24.62%)	54 (29.67%)	11 (13.41%)
61–70 years	90 (34.09%)	62 (34.07%)	28 (34.15%)
> 70 years	77 (29.17%)	45 (24.73%)	32 (39.02%)

Abbreviations: n, sample size; %, percent; SD, standard deviation.

Figure 3 Percentage of detected drug interactions, stratified by gender and body mass index.

Figure 4 Percentage of severe and moderately severe drug interactions by number of interactions.