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Journal of Asthma and Allergy Volume 14, 2021 - Issue
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Case Report

A Case of Anaphylaxis Caused by Major Royal Jelly Protein 3 of Royal Jelly and Its Cross-Reactivity with Honeycomb

Jun-Da Li1 Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, Beijing, People’s Republic of China;3 National Clinical Research Center for Dermatologic and Immunologic Disease, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-5581-5205View further author information
ORCID Icon,
Le Cui1 Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, Beijing, People’s Republic of China;3 National Clinical Research Center for Dermatologic and Immunologic Disease, Beijing, People’s Republic of ChinaView further author information
,
Ying-Yang Xu1 Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, Beijing, People’s Republic of China;3 National Clinical Research Center for Dermatologic and Immunologic Disease, Beijing, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-0583-1925View further author information
ORCID Icon &
Kai Guan1 Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, Beijing, People’s Republic of China;3 National Clinical Research Center for Dermatologic and Immunologic Disease, Beijing, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1555-1557 | Published online: 22 Dec 2021

Figures & data

Figure 1 The results of basophil activation test.

Figure 1 The results of basophil activation test.

Figure 2 Immunoblot and inhibition analysis. The serum-specific IgE bind to royal jelly and honeycomb. Line 1: royal jelly, serum; Line 2: royal jelly, serum co-incubated with honeycomb; Line 3: honeycomb, serum; Line 4: honeycomb, serum co-incubated with royal jelly.

Figure 2 Immunoblot and inhibition analysis. The serum-specific IgE bind to royal jelly and honeycomb. Line 1: royal jelly, serum; Line 2: royal jelly, serum co-incubated with honeycomb; Line 3: honeycomb, serum; Line 4: honeycomb, serum co-incubated with royal jelly.

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