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Journal of Asthma and Allergy Volume 16, 2023 - Issue
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ORIGINAL RESEARCH

Specific IgE Response and Omalizumab Responsiveness in Severe Allergic Asthma

Tomoko Tajiri1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4646-5378View further author information
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Motohiko Suzuki2 Department of Otorhinolaryngology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, Japan;3 Department of Otorhinolaryngology, Nagoya City East Medical Center, Nagoya, Aichi, JapanView further author information
,
Takeo Kutsuna4 Department of Respiratory Medicine, Daido Hospital, Nagoya, Aichi, JapanView further author information
,
Hirono Nishiyama1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-1198-4290View further author information
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Keima Ito1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-9217-6956View further author information
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Norihisa Takeda1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-5210-1642View further author information
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Kensuke Fukumitsu1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0003-1506-7104View further author information
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Yoshihiro Kanemitsu1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-1529-9477View further author information
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Satoshi Fukuda1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-4711-4289View further author information
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Takehiro Umemura1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0001-6732-5625View further author information
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Hirotsugu Ohkubo1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-8538-1150View further author information
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Ken Maeno1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-4561-4044View further author information
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Yutaka Ito1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-1538-5551View further author information
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Tetsuya Oguri1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0002-3796-7915View further author information
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Masaya Takemura1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0003-1486-0987View further author information
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Kosho Yoshikawa4 Department of Respiratory Medicine, Daido Hospital, Nagoya, Aichi, JapanView further author information
&
Akio Niimi1 Department of Respiratory Medicine, Allergy and Clinical Immunology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, JapanORCID Iconhttps://orcid.org/0000-0003-4947-4760View further author information
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Pages 149-157 | Received 16 Oct 2022, Accepted 04 Jan 2023, Published online: 22 Jan 2023

Figures & data

Table 1 Characteristics of Patients and Comparison of Responders with Non-Responders

Figure 1 Comparison of omalizumab response rates between patients with pollinosis and patients with neither pollinosis nor pollen sensitization. *By the chi-squared test between patients with pollinosis and patients with neither pollinosis nor pollen sensitization.

Figure 1 Comparison of omalizumab response rates between patients with pollinosis and patients with neither pollinosis nor pollen sensitization. *By the chi-squared test between patients with pollinosis and patients with neither pollinosis nor pollen sensitization.

Table 2 OR and Associated 95% CIs for the Effectiveness of Omalizumab

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