Implications of Atopic Dermatitis on the Quality of Life of 6–11 Years Old Children and Caregivers (PEDI-BURDEN)

Figures & data

Table 1 Demographic and Clinical Data of the Final Study Population

	AD Group	Non-AD Group
	(N = 160)	(N = 100)
Age	8.8	8.3
Female/Male (%)*	40/60	53/47
Children Comorbidities (%)
Pollen allergies*	52.5	12.0
Dust allergies*	46.2	14.0
Allergic conjunctivitis*	35.0	7.0
Food allergies*	33.1	9.0
Asthma*	23.1	7.0
Chronic rhinosinusitis with nasal polyps*	7.5	2.0
Parents and family comorbidities (%)
Atopic dermatitis*	69.4	15.0
Pollen allergies*	66.2	46.0
Dust allergies*	58.7	43.0
Food allergies*	51.9	21.0
Asthma*	44.4	24.0
Chronic rhinosinusitis with nasal polyps*	15.0	6.0
CDLQI distribution (%)
No effect	2.5	na
Small effect	12.5	na
Moderate effect	30.6	na
Very large effect	28.1	na
Extremely large effect	26.3	na
HRQoL distribution (%)
Quite a lot*	13.1	3.0
A lot*	42.5	5.0
Somewhat*	27.5	5.0
Not Much	10.6	8.0
Not at all*	6.3	79.0
AD treatments (%)^
Topical corticosteroids	55.6	na
Oral antihistamines	29.4	na
Topical non-corticosteroid drugs	22.5	na
Oral corticosteroids	21.9	na
Antibiotics	21.5	na
Calcineurin inhibitors	12.5	na
Immunosuppressant drugs	6.9	na
Biologic drugs	6.3	na
No AD treatment	8.0	na

Notes: *Statistically significant (p≤0.05). ^Treatments refer to the previous week.

Abbreviations: AD, Atopic Dermatitis; na, not applicable.

Figure 1 Limitations and implications on daily activities.

Notes: AD and non-AD related limitations in the AD group vs any health limitation in the non-AD group (A); specific daily limitations in the AD population (B). *Statistically significant (p≤0.05).

Abbreviation: AD, atopic dermatitis.

Figure 2 Emotional burden.

Notes: Emotional burden of atopic dermatitis expressed as positive and negative feelings (A). (B) shows behaviors and beliefs associated with atopic dermatitis. *Statistically significant (p≤0.05).

Abbreviation: AD, atopic dermatitis.

Figure 3 Sleep impairment and daily drowsiness.

Notes: Quality of sleep for parents and children with or without atopic dermatitis over the past year (A). The average score is on a 0 to 10 scale. Number of nights with poor sleep (B) and days with drowsiness (C). ^a,^b,^c,*,**,***,****Statistically significant (p≤0.05).

Abbreviation: AD, atopic dermatitis.

Figure 4 Absenteeism and presenteeism.

Notes: Absenteeism as number of days of school missed over the past 12 months (A) and presenteeism as number of days with decreased focus/functionality (B) due to atopic dermatitis or any/any other health-related issue over the past 12 months. Data expressed as percentages and average. *,**Statistically significant (p≤0.05).

Abbreviation: AD, atopic dermatitis.