Platelet Transfusion: And Update on Challenges and Outcomes

Figures & data

Table 1 Prophylactic Platelet Transfusion: Comparative Thresholds for Invasive Procedures and Surgery According to Different Guidelines

Procedures	Guidelines
	AABB^Citation7	ASCO^Citation12	BSH^Citation11	SETS^Citation8	SIMTI^Citation4
Major non-neuraxial surgery	≥ 50 x 10^9/L	40-50 x 10^9/L	> 50 x 10^9/L	> 50 x 10^9/L	> 50 x 10^9/L
Lumbar puncture	≥ 50 x 10^9/L	NR*	≥ 40 x 10^9/L	> 20 x 10^9/L	> 50 x 10^9/L
Venus central lines placement	≥ 20 x 10^9/L	≥ 20 x 10^9/L	≥ 20 x 10^9/L	> 20 x 10^9/L	> 50 x 10^9/L
Neurosurgery or ophthalmic surgery	NR	NR	> 100 x 10^9/L	> 80 x 10^9/L	> 100 x 10^9/L
Percutaneous liver biopsy	NR	NR	> 50 x 109/L	NR	> 50 x 10^9/L
Insertion/removal of epidural catheter	NR	NR	≥ 80 x 109/L	NR	> 50 x 10^9/L
Bone marrow aspirate or trephine biopsy	NR	≥ 20 x 10^9/L	Do not give platelet transfusion	NR	NR
Traction removal of tunneled CVCs	NR	NR	Do not give platelet transfusion	> 20 x 10^9/L	> 50 x 10^9/L
Cataract surgery	NR	NR	Do not give platelet transfusion	NR	NR
Chronic thrombocytopenia from central origin without active treatment	NR	Do not give platelet transfusion	Do not give platelet transfusion	> 5 x 10^9/L	NR
Immune thrombocytopenia	NR	NR	Do not give platelet transfusion	Do not give platelet transfusion	NR

Note: NR* no recommendation is given.

Abbreviations: AABB, American Association of Blood Banks, ASCO, American Society of Clinical Oncology; BSH, British Society of Haematology; SETS, Sociedad Española de Transfusión Sanguínea y Terapia celular; SIMTI, Italian Society of Transfusion Medicine and Immunohematology.

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