Proportion of Acute Transfusion Reaction and Associated Factors Among Adult Transfused Patients at Felege Hiwot Compressive Referral Hospital, Bahir Dar, Northwest Ethiopia: A Cross-Sectional Study

Figures & data

Table 1 Socio-Demographic Characteristics of Transfused Participants at FHCRH from February to April 2019 (N =384)

Variable		Frequency N (%)
Sex	Male	151 (39.3%)
	Female	233 (60.7%)
Residence	Urban	126 (32.8%)
	Rural	258 (67.2%)
Marital status	Single	64 (16.7%)
	Married	293 (76.3%)
	Widowed	9 (2.3%)
	Divorced	18 (4.7%)
Age	< 65	368 (95.8%)
	≥ 65	16 (4.2%)
	Median age 31

Table 2 Clinical Characteristics of Transfused Patients at FHCRH February to April 2019

Characteristics		Frequency (%)
Transfusion history (n = 384)	No	221 (57.6)
	Yes	163 (42.4)
Transfusion history episode (N = 384)	No	221 (57.6)
	One	85 (22.1)
	Two	48 (12.5)
	Three and more	30 (7.8)
Pregnancy history (n = 233)	No	36 (15.45)
	Yes	197 (84.55)
Gravidae (n = 233)	No	36 (15.45)
	One	30 (12.88)
	Two	36 (15.45)
	Three or more	131 (56.22)
History of abortion (n = 233)	No	181 (77.68)
	Yes	52 (22.32)
Frequency of abortion (n = 233)	No	181 (77.68)
	One	33 (14.16)
	Two	10 (4.29)
	Three and more	9 (3.86)
Primary diagnosis (n=380)	Maternal complications	136 (35.4)
	Trauma, orthopedic and surgical case	54 (14.1)
	Chronic disease	52 (13.5)
	Hematological cases	65 (16.9)
	Gastrointestinal bleeding	23 (6.0)
	Other medical cases	54 (14.1)

Table 3 Type and Characteristics of Transfused Blood Component with Frequency of Transfused Patients at FHCRH, February to April 2019 (N =384)

Blood Component Characteristics		Transfused Patient Frequency N (%)
Blood component type	Whole blood	364 (94.8%)
	CRC	8 (2.1%)
	Platelet	5 (1.3%)
	Whole blood and platelet	4 (1.0%)
	Whole blood and CRCs	3 (0.8%)
Storage time	Less than 14 days	228 (59.4%)
	14 days and more	156 (40.6%)
Number of unit transfused	One	227 (59.11%)
	Two	100 (26.04%)
	≥ 3 and more	57 (14.84%)
Total units transfused		638

Table 4 Reaction Incidence and Type Among Adult Transfused Patients at FHCRH, February to April 2019 (N =384)

Incidence of Reaction and Type		Frequency	%
Reaction proportion (N = 384)	No	364	94.8
	Yes	20	5.2
Reaction type (n = 20)	FNHTR	6	30
	Allergic	13	65
	Other alloantibody incompatibilities	1	5
	Total	20	100

Table 5 Bivariable and Multivariable Binary Logistic Regression Analysis of Associated Factors of ATRs Among Adult Transfused Patients at FHCRH, February to April 2019

Variable		ATR		COR(95% CI)	● AOR(95% CI)	P-value
		Developed n (%)	Not-Developed n (%)
Sex (n=384)	Mae	6 (4%)	145 (96%)	1
	Female	14 (6%)	219 (94%)	1.5 (0.6–4.1)		0.384
-Age (year) (n=384)	18 −31	9 (4.7%)	183 (95.3%)	1
	≥32	11 (5.7%)	181 (94.3%)	1.24(0.5 −3.05)		0.647
Blood component (n=384)	Whole	18 (4.9%)	346 (95.1%)	1
	Other	2 (10%)	18 (90%)	2.14 (0.46–9.2)		0.333
Transfusion history (n=384)	No	6 (2.7%)	215 (97.3%)	1	1
	Yes	14 (8.6%)	149 (91.4%)	3.4 (1.3–9.0)	3.4 (1.2–9.7)	0.020
Pregnancy history (n=233)	No	1 (2.8%)	35 (97.2%)	1
	Yes	13 (6.6%)	184 (93.4%)	2.5 (0.31–19)		0. 390
Abortion history (n=233)	No	7 (3.9%)	174 (96.1%)	1	1
	Yes	7 (13.5%)	45 (86.5%)	3.9 (1.3 −11.6)	5.0 (1.5–16.4)	0.008
Storage time(in days) (n=384)	<14 s	5 (2.2%)	223 (97.8%)	1	1
	≥14	15 (9.6%)	141 (90.4%)	4.7 (1.7–13.3)	5.1 (1.7–15.2)	0.003
Transfused units (n=384)	< 3 units	12 (3.7%)	315 (96.3%)	1	1
	≥ 3 units	8 (14%)	49 (86%)	4.3 (1.7–11)	4.1 (1.5–11.2)	0.007

Note: Pregnancy history and Abortion history were analyzed from female study participants.

Abbreviations: COR, crude odd ratio; AOR, adjusted odds ratio.