The Need for Comprehensive Care for Persons with Chronic Immune Thrombocytopenic Purpura

Figures & data

Figure 1 Historical comparison of hemophilia and cITP.

Abbreviations: cITP, chronic immune thrombocytopenic purpura; IVIG, intravenous immunoglobulin; HIV, human immunodeficiency virus; HBV, hepatitis B virus; HCV, hepatitis C virus; TPO, thrombopoietin; Syk, spleen tyrosine kinase; mAbs, monoclonal antibodies.

Table 1 Comparison of Clinical and Non-Clinical Aspects of Hemophilia and cITP

	Hemophilia	cITP
Age Affected	Beginning at Birth	Any Age
Duration	Lifelong	Typically Lifelong Once Diagnosed
Main Sites of Bleeding
Joints	Common	Rare
Mucocutaneous	Common	Common
Gastrointestinal	Common	Common
Genitourinary	Common	Common
CNS	Uncommon	Uncommon
Treatment costs	Very expensive	Very expensive
Health-related Quality of Life	Pain, hemarthrosis, anxiety, ADL limitations, work/school absenteeism, social functioning, treatment related burden/concerns^Citation36	Fatigue, anxiety, depression, ADL limitations, work/school absenteeism, social isolation, treatment related burden/concerns^Citation43^–^Citation45
Advocacy	International: WFH National: NHF, HFA, HA State: National Organization Chapters Local: HTCs	National: PDSA Local: Affiliates of PDSA
Comprehensive Care Centers	National network of HTCs	None

Abbreviations: cITP, chronic immune thrombocytopenia purpura; ICH, intracranial hemorrhage; CNS, central nervous system; ADL, activities of daily living; WFH, World Federation of Hemophilia; NHF, National Hemophilia Foundation; HFA, Hemophilia Federation of America; HA, Hemophilia Alliance; HTCs, Hemophilia Treatment Centers; PDSA, Platelet Disorder Support Association.

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