Evaluation of Hematological Parameters of Helicobacter pylori-Infected Adult Patients at Southern Ethiopia: A Comparative Cross-Sectional Study

Figures & data

Table 1 Socio-Demographic Variables Distribution of H. pylori-Infected Patients and Controls at Wachemo University Nigist Eleni Mohammed Memorial Referral Hospital, 2019

Variables	Categories	H. pylori-Infected Group	Controls Group
Gender	Female	94(50.3%)	94(50.3%)
	Male	93(49.7%)	93(49.7%)
Age in years	18–27	62(33.2%)	76(40.6%)
	28–37	72(38.5%)	66(35.3%)
	38–47	49(26.2%)	42(22.5%)
	≥48	4(2.1%)	3(1.6%)
Residence	Urban	78(41.7%)	80(42.8%)
	Rural	109(58.3%)	107(57.2%)
Educational status	Illiterate	56(29.9%)	44(23.5%)
	Primary	31(16.6%)	24(12.8%)
	Secondary	54(28.9%)	65(34.8%)
	Higher level	46(24.6%)	54(28.9%)

Abbreviation: H. pylori, Helicobacter pylori.

Table 2 Comparisons of Mean Values of RBC Parameters of H. pylori-Infected Patients and Controls at Wachemo University Nigist Eleni Mohammed Memorial Referral Hospital, 2019

RBC Parameters	H. pylori-Infected Group Mean ±SD	Control Group Mean ±SD	p-value
Hgb g/dl	13.32 ±1.56	14.25 ±1.89	<0.001
RBCx10^6/µL	4.39 ±0.46	4.79 ±0.61	<0.001
HCT (%)	40.38 ±4.40	45.71 ±5.31	<0.001
MCV(fl)	88.03 ±5.44	89.64±4.84	0.003
MCH(pg)	28.33 ±2.18	28.94 ±2.19	0.008
MCHC g/dl	31.99 ±1.30	32.38 ±1.45	0.006
RDW (%)	14.31±1.45	13.92±1.12	0.003

Note: P-value <0.05 is considered statistically significant.

Abbreviations: fl, femtoliters; g/dl, gram per deciliter; Hgb, hemoglobin; H. pylori, Helicobacter pylori, RBC, red blood cell; HCT, hematocrit; MCV, mean cell volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; µL, microliters; %, percentage; pg, pictogram; RDW, red blood cell distribution width; SD, standard deviation.

Table 3 The Proportion of H. pylori-Infected Patients (n=187) with Low, Normal, and High Values of RBC Parameters at Wachemo University Nigist Eleni Mohammed Memorial Referral Hospital, 2019

RBC Parameters	Categories	Frequency (%)	Reference Range
Hgb (g/dl)	Low	26(13.9%)	Male 11.5–18
	Normal	161(86.1%)	Female 11–16.7
RBCx10^6/µL	Low	13(7%)	Male 3.53–6.93
	Normal	174(93%)	Female 3.45–6.25
HCT (%)	Low	12(6.4%)	Male 36.2–58.6
	Normal	175(93.6%)	Female 32.1–56.6
MCV(fl)	Low	34(18.2%)	Male 85–100
	Normal	148(79.1%)	Female 85–100
	High	5(2.7%)
MCH(pg)	Low	27(14.4%)	Male 26.6–33.3
	Normal	159(85%)	Female 25.8–32.8
	High	1(0.5)
MCHC g/dl	Low	4(2.1%)	Male 29.5–34.4
	Normal	179(95.7%)	Female 28.5–34.4
	High	4(2.1%)
RDW (%)	Low	1(0.5%)	Male 12–17
	Normal	180(96.3%)	Female 12–17
	High	6(3.2%)

Abbreviations: fl, femtoliters; g/dl, gram per deciliter; Hgb, hemoglobin; RBC, red blood cell; HCT, hematocrit; MCV, mean cell volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; µL, microliters; %, percentage; pg, pictogram; RDW, red blood cell distribution width.

Table 4 Correlation Analysis of RBC Parameters with Predictors Among H. pylori-Infected Patients at Wachemo University Nigist Eleni Mohammed Memorial Referral Hospital, 2019

Predictors	RBC		Hgb		HCT		MCV		MCH		MCHC		RDW
	r	p	R	p	R	p	r	p	r	p	r	p	r	p
Age	0.01	0.8	0.05	0.26	0.02	0.6	0.02	0.6	0.02	0.5	0.2	0.6	0.05	0.3
Gender	0.01	0.9	0.06	0.18	0.15	0.003	−0.1	0.01	0.07	0.1	0.5	0.2	0.1	0.04
Residence	0.08	0.1	−0.12	0.01	−0.11	0.02	0.05	0.2	0.08	0.1	0.1	0.5	0.1	0.04
BMI	0.03	0.4	0.08	0.1	0.03	0.5	0.04	0.4	0.11	0.02	0.1	0.03	0.02	0.5
SBP	0.13	0.01	0.14	0.006	0.07	0.14	0.02	0.6	−0.1	0.02	0.7	0.1	0.03	0.4
DBP	0.001	0.9	0.02	0.6	0.02	0.6	0.01	0.7	0.01	0.8	0.7	0.1	−0.1	0.04

Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; Hgb, hemoglobin; RBC, red blood cell; HCT, hematocrit; MCV, mean cell volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; p, the p-value for correlation; RDW, red blood cell distribution width; r, Pearson correlation coefficient.