Figures & data
Figure 1 Imatinib seems to work in systemic sclerosis patients through the inhibition of the TGF-β and PDGF signaling pathway via c-Abl and directly by blocking PDGFR, which results in a decrease of gene transcription and consequently in a decrease in collagen production.
![Figure 1 Imatinib seems to work in systemic sclerosis patients through the inhibition of the TGF-β and PDGF signaling pathway via c-Abl and directly by blocking PDGFR, which results in a decrease of gene transcription and consequently in a decrease in collagen production.](/cms/asset/4d40d172-70a0-4341-a6cb-fde19cf86343/djep_a_26894_f0001_c.jpg)