Hepatitis C Antiviral Therapy In Patients With Successfully Treated Hepatocellular Carcinoma: Dancing With Wolves

Figures & data

Table 1 Summary Of The Predictors Of HCC Recurrence Post DAAs

Study	Journal/Year	Country	Study Design	HCC Recurrence Rate (%)	Predictors Of HCC Recurrence	Median Follow Up (Months)	Sample Size
Conti et al^Citation22	J Hepatol, 2016	Italy	Retrospective	28.8	Age, liver stiffness	12	59
Petta et al^Citation41	Alimentary Pharmacology and Therapeutics, 2017	Italy	Retrospective	27.6	Baseline AFP, bilirubin and creatinine levels	18	58
Cabibbo et al^Citation30	Alimentary Pharmacology and Therapeutics, 2017	Italy	Prospective	21	Previous recurrence, tumor size	9	143
Nagata et al^Citation27	J Hepatol, 2017	Japan	Retrospective	29	SVR, AFP, WFA-M2BP	27.6	83
El Kassas et al^Citation5	Journal of Viral Hepatitis, 2018	Egypt	Prospective	37.7	Exposure to DAAs, Child-Pugh score and presence of gastro esophageal varices	16	53
Ogawa et al^Citation31	Alimentary Pharmacology and Therapeutics, 2018	Japan	Prospective	16.5	Baseline level of AFP, treatment modality and increased number of HCC nodules	17	152
Mashiba et al^Citation33	PLoS ONE, 2018	Japan	Retrospective	N/A	Albumin, PT, AST, AFP at end of antiviral treatment, duration from last HCC intervention to starting antiviral therapy, number of past treatments for HCC, clinical HCC staging, and status of SVR	24	368
Yasui et al^Citation43	Hepatology Research, 2018	Japan	Retrospective	44	AFP level	N/A	49

Abbreviations: DAA, direct-acting antiviral agents; AFP, alpha-fetoprotein; HCC, hepatocellular carcinoma; SVR, sustained virological response; NA, not available.

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