164
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Improved Survival in At-Risk Patients Undergoing Surveillance for Hepatocellular Carcinoma – A Nationwide Swedish Register-Based Study

ORCID Icon, ORCID Icon, , ORCID Icon, &
Pages 1573-1586 | Received 05 May 2023, Accepted 24 Aug 2023, Published online: 19 Sep 2023

Figures & data

Table 1 Underlying Etiology of Hepatocellular Carcinoma. Presented as Numbers and Valid Percentages

Figure 1 Inclusion flow chart.

Abbreviation: HCC, hepatocellular carcinoma.
Figure 1 Inclusion flow chart.

Table 2 Patient Characteristics for Included Patients

Figure 2 Kaplan–Meier curve showing estimated lead-time adjusted survival. Non-surveillance group including only patients with a presumed surveillance indication.

Figure 2 Kaplan–Meier curve showing estimated lead-time adjusted survival. Non-surveillance group including only patients with a presumed surveillance indication.

Table 3 Multivariable Cox Regression Analyses for Overall Mortality, Corrected for Lead-Time Bias with a Sojourn Time of 270 Days

Figure 3 Survival curve from multivariable Cox regression analysis in patients with a follow-up time of ≥ 36 months. Non-surveillance group including only patients with a presumed surveillance indication. Adjusted for age, sex, performance status, etiology and presence of diabetes. Lead-time adjusted with a sojourn time of 270 days.

Figure 3 Survival curve from multivariable Cox regression analysis in patients with a follow-up time of ≥ 36 months. Non-surveillance group including only patients with a presumed surveillance indication. Adjusted for age, sex, performance status, etiology and presence of diabetes. Lead-time adjusted with a sojourn time of 270 days.

Figure 4 Comparisons between surveillance groups for meeting the UCSF-criteria, receiving curative treatment and presence of extrahepatic spread. Non-surveillance group including only those with a presumed surveillance indication.

Abbreviation: UCSF, University of California San Francisco.
Figure 4 Comparisons between surveillance groups for meeting the UCSF-criteria, receiving curative treatment and presence of extrahepatic spread. Non-surveillance group including only those with a presumed surveillance indication.

Table 4 Estimated Median Survival Time in Months for Specific Etiology of Hepatocellular Cancer. Only Patients with Known Etiologies Included