Figures & data
Abbreviations: IGFBP, insulin-like growth factor binding protein; IGF-IR, IGF-I receptor; IGF-IIR, IGF-II receptor.
Abbreviations: CLD, chronic liver disease; GH, growth hormone; HCC, hepatocellular carcinoma; IGF-I, insulin-like growth factor-I; GHR, GH receptor; IGFBP, IGF binding protein; IGFR, IGF receptor.
Abbreviations: IGFBP, IGF binding protein; IGF-IR, IGF-I receptor; MMP-9, matrix metallopeptidase-9; uPAR, urokinase plasminogen activator receptor; ERK, extracellular signal-regulated kinases; ECM, extracellular matrix; SOS, son of sevenless; GRB2, Growth factor receptor-bound protein 2; SHC, src homology/α-collagen related protein; MEK, mitogen-activated protein kinase/extracellular signal-regulated kinase; mTOR, mammalian target of rapamycin; PI3K, phosphatidylinositol 3-kinase.
Notes: (A) Training cohort (n=310). (B) Validation cohort (n=155). The first letter for each group represents the CTP class; the second letter, the IGF-CTP class (eg, group AB represents patients classified as CTP class A and IGF-CTP class B).
Abbreviation: IGF, insulin-like growth factor.
Abbreviation: IGF, insulin-like growth factor.